SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases (Q24291801)

negative regulation of protein catabolic process

GOA release 2020-03-11

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Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Y S Askew

1

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S C Pak

2

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C J Luke

3

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D J Askew

4

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S Cataltepe

5

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D R Mills

6

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H Kato

7

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J Lehoczky

8

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K Dewar

9

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B Birren

10

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G A Silverman

Journal of Biological Chemistry

11

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language of work or name

English

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publication date

28 December 2001

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published in

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volume

276

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issue

52

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page(s)

49320-30

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cites work

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Chromosomal Mapping of the Gene (PI9) Encoding the Intracellular Serpin Proteinase Inhibitor 9 to 6p25 by Fluorescencein SituHybridization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Human Ovalbumin Serpin Evolution: Phylogenic Analysis, Gene Organization, and Identification of New PI8-Related Genes Suggest That Two Interchromosomal and Several Intrachromosomal Duplications Generated the Gene Clusters at 18q21–q23 and 6p25

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

The ovalbumin family of serpin proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Trypsin complexed with alpha 1-proteinase inhibitor has an increased structural flexibility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Yeast artificial chromosome cloning of a two-megabase-size contig within chromosomal band 18q21 establishes physical linkage between BCL2 and plasminogen activator inhibitor type-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Multiple sequence alignment with Clustal X

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Determination of the operational molarity of solutions of bovine α-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

The covalent nature of the human antithrombin III--thrombin bond

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

A serpin-induced extensive proteolytic susceptibility of urokinase-type plasminogen activator implicates distortion of the proteinase substrate-binding pocket and oxyanion hole in the serpin inhibitory mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Regulation of pro-apoptotic leucocyte granule serine proteinases by intracellular serpins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Squamous cell carcinoma antigen 2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

MENT, a heterochromatin protein that mediates higher order chromatin folding, is a new serpin family member

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Cloning and expression of a novel hepatitis B virus-binding protein from HepG2 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

The serpin inhibitory mechanism is critically dependent on the length of the reactive center loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

An 18q- syndrome breakpoint resides between the duplicated serpins SCCA1 and SCCA2 and arises via a cryptic rearrangement with satellite III DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Alpha-2-antiplasmin: a serpin with two separate but overlapping reactive sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Genetic transfer and expression of reconstructed yeast artificial chromosomes containing normal and translocated BCL2 proto-oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Human plasma proteinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108879200

7 January 2021