Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride (Q23921533)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15878868%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride (English)

2 references

12 July 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15878868%20AND%20SRC:MED&resulttype=core&format=json

NIOSH Health Effects Laboratory Division

11 January 2020

sponsor

object named as

HELD

1 reference

25 September 2023

1 reference

19 July 2017

2 references

19 July 2017

29 March 2020

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29 March 2020

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29 March 2020

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29 March 2020

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29 March 2020

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Sreekumar Othumpangat

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15878868%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

2

Michael Kashon

1 reference

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11 January 2020

author name string

Pius Joseph

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15878868%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

language of work or name

English

0 references

publication date

5 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15878868%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

11 January 2020

published in

1 reference

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11 January 2020

volume

280

1 reference

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11 January 2020

issue

26

1 reference

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11 January 2020

page(s)

25162-25169

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on focus list of Wikimedia project

11 January 2020

Wikimedia–NIOSH collaboration

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cites work

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

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Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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The mRNA 5' cap-binding protein, eIF-4E, cooperates with v-myc or E1A in the transformation of primary rodent fibroblasts

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Ras mediates translation initiation factor 4E-induced malignant transformation

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Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas

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Oncogenic potential of mouse translation elongation factor-1 delta, a novel cadmium-responsive proto-oncogene

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Up-regulation of expression of translation factors--a novel molecular mechanism for cadmium carcinogenesis

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Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo

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Involvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo

21 January 2018

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Cadmium induces c-myc, p53, and c-jun expression in normal human prostate epithelial cells as a prelude to apoptosis

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Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species

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Cadmium-induced apoptosis of primary epithelial lung cells: involvement of Bax and p53, but not of oxidative stress

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Apoptosis and necrosis: two distinct events induced by cadmium in cortical neurons in culture.

21 January 2018

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Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor

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Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcription

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Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis

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Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

21 January 2018

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Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

21 January 2018

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Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

21 January 2018

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Activation of the c-myc gene by translocation: a model for translational control

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cadmium induces apoptosis partly via caspase-9 activation in HL-60 cells

21 January 2018

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7 January 2021

Elevated expression of eIF4E and FGF-2 isoforms during vascularization of breast carcinomas

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1074/JBC.M414303200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15878868%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

0 references

1 reference