venetoclax &#160; Béarla (Q23671272)

https://www.chemicalprobes.org/venetoclax

struchtúr ceimiceach

Venetoclax.svg
512 × 255; 16 KB

0 references

mais

867.318096 aonad maise adamhaí

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

ABT-199 (Béarla)

3 Deireadh Fómhair 2016

foirmle cheimiceach

C₄₅H₅₀ClN₇O₇S

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

ABT-199 (Béarla)

20 Samhain 2016

CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

ABT-199 (Béarla)

20 Samhain 2016

active ingredient in ^Béarla

Venclyxto ^Béarla

1 reference

European Medicines Agency product number ^Béarla

EMEA/H/C/004106

http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/004106/human_med_002045.jsp

22 Márta 2017

Venclexta ^Béarla

1 reference

RxNorm ^Béarla

RxNorm ID ^Béarla

1747562

14 Feabhra 2018

spriocghalar

mantle cell lymphoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

chronic lymphocytic leukemia ^Béarla

1 reference

2 Deireadh Fómhair 2018

acute myeloid leukemia ^Béarla

1 reference

siondróm miailidiospláiseach

2 Deireadh Fómhair 2018

1 reference

2 Deireadh Fómhair 2018

Liomfóma neamh-Hodgkin

1 reference

2 Deireadh Fómhair 2018

B-cell lymphoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

diffuse large B-cell lymphoma ^Béarla

1 reference

2 Deireadh Fómhair 2018

chronic lymphocytic leukemia ^Béarla

am tosaigh

11 Aibreán 2016

approved by ^Béarla

Riarachán Bia is Drugaí

1 reference

Inxight: Drugs Database ^Béarla

2 Samhain 2018

https://drugs.ncats.io/drug/N54AIC43PW

http://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208573s000lbl.pdf

physically interacts with ^Béarla

BCL2 apoptosis regulator ^Béarla

ról an ábhair

reaction inhibitor ^Béarla

1 reference

Open Targets Platform ^Béarla

14 Lúnasa 2023

https://platform.opentargets.org/drug/CHEMBL3137309

LiverTox likelihood score ^Béarla

LiverTox toxicity likelihood category E ^Béarla

1 reference

LiverTox ^Béarla

8 Aibreán 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Venetoclax

last update ^Béarla

4 Aibreán 2017

ról an ábhair

xenobiotic-transporting ATPase inhibitor ^Béarla

1 reference

NDF-RT ^Béarla

NDF-RT ID ^Béarla

5 Márta 2018

1 reference

Medical Subject Headings ^Béarla

MeSH descriptor ID ^Béarla

C579720

InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)

15 Márta 2018

catagóir Commons

Venetoclax

0 references

Identifiers

InChI

1 reference

PubChem ^Béarla

PubChem CID ^Béarla

ABT-199 (Béarla)

20 Samhain 2016

InChIKey ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

ABT-199 (Béarla)

20 Samhain 2016

ChEBI release 2020-09-01 ^Béarla

uimhir CAS

1257044-40-8

2 references

Global Substance Registration System ^Béarla

UNII ^Béarla

N54AIC43PW

venetoclax (Béarla)

20 Samhain 2016

InChIKey ^Béarla

CAS Common Chemistry ^Béarla

8 Aibreán 2021

https://commonchemistry.cas.org/detail?cas_rn=1257044-40-8

ChemSpider ID ^Béarla

29315017

1 reference

ChemSpider ^Béarla

ChemSpider ID ^Béarla

29315017

Venetoclax (Béarla)

20 Samhain 2016

PubChem CID ^Béarla

2 references

PubChem ^Béarla

PubChem CID ^Béarla

ABT-199 (Béarla)

20 Samhain 2016

InChIKey

InChIKey ^Béarla

ChEBI ID ^Béarla

133021

mapping relation type ^Béarla

meaitseáil chruinn

2 references

ChEBI release 2019-10-02 ^Béarla

InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)

International Chemical Identifier ^Béarla

InChI

ChEMBL ID ^Béarla

CHEMBL3137309

1 reference

ChEMBL ^Béarla

ChEMBL ID ^Béarla

CHEMBL3137309

VENETOCLAX (Béarla)

bunaithe ar chur chuige heorastúil

20 Samhain 2016

SureChEMBL ID ^Béarla

SCHEMBL523816

2 references

inferred from InChIKey ^Béarla

InChIKey

InChIKey ^Béarla

UniChem compound ID ^Béarla

27308331

1 reference

UniChem ^Béarla

DSSTox substance ID ^Béarla

DTXSID30154863

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard ^Béarla

InChIKey

InChIKey ^Béarla

DSSTOX compound identifier ^Béarla

DTXCID0077354

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LiverTox ID ^Béarla

Venetoclax

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EC number ^Béarla

820-130-9

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.254.611

27 Nollaig 2018

2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide (amorphous) (Béarla)

quotation ^Béarla

CAS no.: 1257044-40-8 (Béarla)

ECHA Substance Infocard ID ^Béarla

100.254.611

1 reference

ECHA Substance Infocard database ^Béarla

ECHA Substance Infocard ID ^Béarla

100.254.611

27 Nollaig 2018

2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide (amorphous) (Béarla)

quotation ^Béarla

CAS no.: 1257044-40-8 (Béarla)

ATC code ^Béarla

L01XX52

0 references

Guide to Pharmacology Ligand ID ^Béarla

8318

1 reference