Stromal interaction molecule 1 (Q2356710)

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mammalian protein found in Homo sapiens
  • stromal interaction molecule 1
  • uniprot:Q13586
  • STIM1
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Language Label Description Also known as
English
Stromal interaction molecule 1
mammalian protein found in Homo sapiens
  • stromal interaction molecule 1
  • uniprot:Q13586
  • STIM1

Statements

molecular function
protein binding
determination method
IPI
24 references
retrieved
10 September 2018
stated in
TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Mitochondria control store-operated Ca2+ entry through Na+ and redox signals
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
An EB1-binding motif acts as a microtubule tip localization signal
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Calsequestrin-1 Regulates Store-Operated Ca2+ Entry by Inhibiting STIM1 Aggregation
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Junctate is a Ca2+-sensing structural component of Orai1 and stromal interaction molecule 1 (STIM1)
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca²⁺ influx
GOA
curator
UniProt
UniProt protein ID
Q13586
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Modulation of STIM1 and capacitative Ca2+ entry by the endoplasmic reticulum luminal oxidoreductase ERp57
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Atomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Calmodulin binding to the polybasic C-termini of STIM proteins involved in store-operated calcium entry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
identical protein binding
determination method
IPI
6 references
retrieved
10 September 2018
stated in
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Atomic force microscopy (AFM) imaging suggests that stromal interaction molecule 1 (STIM1) binds to Orai1 with sixfold symmetry
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
retrieved
10 September 2018
stated in
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13586&geneProductId=UniProtKB:Q13586
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE STIM1 202764 at fs.png
732 × 530; 11 KB
0 references

Identifiers

RefSeq protein ID
 
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                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q2356710&oldid=2022903793"