Mitochondrial DNA stress primes the antiviral innate immune response (Q23030015)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25642965%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

4

Michal C Tal

Michal C

Tal

1 reference

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1 June 2020

12

James R Smiley

James R

Smiley

1 reference

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1 June 2020

14

Akiko Iwasaki

Akiko

Iwasaki

1 reference

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1 June 2020

author name string

William Khoury-Hanold

2

William

Khoury-Hanold

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25642965%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Matthew Staron

3

Matthew

Staron

1 reference

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1 June 2020

Cristiana M Pineda

5

Cristiana M

Pineda

1 reference

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1 June 2020

Sabine M Lang

6

Sabine M

Lang

1 reference

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1 June 2020

Megan Bestwick

7

Megan

Bestwick

1 reference

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1 June 2020

Brett A Duguay

8

Brett A

Duguay

1 reference

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1 June 2020

Nuno Raimundo

9

Nuno

Raimundo

1 reference

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1 June 2020

Donna A MacDuff

10

Donna A

MacDuff

1 reference

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1 June 2020

Susan M Kaech

11

Susan M

Kaech

1 reference

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1 June 2020

Robert E Means

13

Robert E

Means

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25642965%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Gerald S Shadel

15

Gerald S

Shadel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25642965%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

0 references

publication date

23 April 2015

0 references

published in

Nature

1 reference

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1 June 2020

volume

520

1 reference

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1 June 2020

issue

7548

1 reference

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1 June 2020

page(s)

553-557

1 reference

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describes a project that uses

1 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4409480/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Cytosolic sensing of viruses

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

EXOG, a novel paralog of Endonuclease G in higher eukaryotes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC(Min/+) mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

TM4: a free, open-source system for microarray data management and analysis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

7 April 2017

Mitochondria and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

In D-loop: 40 years of mitochondrial 7S DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Elimination of mitochondrial DNA is not required for herpes simplex virus 1 replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Molecular basis of DNA recognition in the immune system

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Interferome v2.0: an updated database of annotated interferon-regulated genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

A vaccine strategy that protects against genital herpes by establishing local memory T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

A neuron-specific role for autophagy in antiviral defense against herpes simplex virus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Leukocyte mitochondrial DNA alteration in systemic lupus erythematosus and its relevance to the susceptibility to lupus nephritis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Interferon-stimulated genes and their antiviral effector functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondria in innate immune responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Underexpression of mitochondrial-DNA encoded ATP synthesis-related genes and DNA repair genes in systemic lupus erythematosus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Placental viral infection sensitizes to endotoxin-induced pre-term labor: a double hit hypothesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Functional organization of mammalian mitochondrial DNA in nucleoids: history, recent developments, and future challenges.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Crude subcellular fractionation of cultured mammalian cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Lymphocytic choriomeningitis virus (LCMV): propagation, quantitation, and storage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Epstein-Barr virus immediate-early protein Zta co-opts mitochondrial single-stranded DNA binding protein to promote viral and inhibit mitochondrial DNA replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondrial-nuclear communications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Herpes simplex virus eliminates host mitochondrial DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Interferon-alpha in systemic lupus erythematosus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Vesicular stomatitis virus glycoprotein containing the entire green fluorescent protein on its cytoplasmic domain is incorporated efficiently into virus particles.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Incorporation of the green fluorescent protein into the herpes simplex virus type 1 capsid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Herpes simplex virus UL12.5 targets mitochondria through a mitochondrial localization sequence proximal to the N terminus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

A mouse model for studies of mucosal immunity to vaginal infection by herpes simplex virus type 2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4409480

Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25642965

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE14156

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25642965%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

1048355724

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25642965%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

2 references