Chymase 1 (Q22677549)

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mammalian protein found in Homo sapiens

chymase, mast cell
alpha-chymase
chymase, heart
CMA1
chymase 1 preproprotein transcript E
mast cell protease I
chymase 1 preproprotein transcript I
chymase 1, mast cell
chymase

Language	Label	Description	Also known as
English	Chymase 1	mammalian protein found in Homo sapiens	chymase, mast cell alpha-chymase chymase, heart CMA1 chymase 1 preproprotein transcript E mast cell protease I chymase 1 preproprotein transcript I chymase 1, mast cell chymase

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

peptidase S1A, chymotrypsin family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23946

Peptidase S1, PA clan

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23946

Serine proteases, trypsin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, histidine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, serine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptide binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

serine-type endopeptidase activity

determination method

5 references

8 April 2019

Cloning of the gene and cDNA for human heart chymase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Determination of the primary structures of human skin chymase and cathepsin G from cutaneous mast cells of urticaria pigmentosa lesions

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

serine-type peptidase activity

determination method

4 references

8 April 2019

Structure, chromosomal assignment, and deduced amino acid sequence of a human gene for mast cell chymase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

secretory granule

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23946&geneProductId=UniProtKB:P23946

determination method

extracellular region

determination method

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23946&geneProductId=UniProtKB:P23946

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23946&geneProductId=UniProtKB:P23946

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23946&geneProductId=UniProtKB:P23946

determination method

17 October 2017

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23946&geneProductId=UniProtKB:P23946

determination method

extracellular region

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

extracellular space

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

secretory granule

determination method

1 reference

8 April 2019

Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

biological process

peptide metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

angiotensin maturation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

positive regulation of angiogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

regulation of inflammatory response

determination method

1 reference

8 April 2019

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

midbrain development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

cellular response to glucose stimulus

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

basement membrane disassembly

determination method

1 reference

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23946

determination method

serine proteases, trypsin family, histidine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23946

serine proteases, trypsin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23946

Serine proteases, trypsin family, serine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23946

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000206446

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000206446

ENSP00000250378

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000250378

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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