3-hydroxyanthranilate 3,4-dioxygenase (Q22677454)

http://www.ebi.ac.uk/interpro/protein/P46952

3-hydroxyanthranilate 3, 4-dioxygenase, metazoan

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P46952

RmlC-like jelly roll fold

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P46952

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

3-hydroxyanthranilate 3,4-dioxygenase activity

7 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

16 July 2018

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

16 July 2018

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

16 July 2018

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

3 references

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

electron transfer activity

IPI

1 reference

8 April 2019

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

NAS

oxidoreductase activity

1 reference

8 April 2019

2 references

27 March 2018

Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

27 March 2018

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

3-hydroxyanthranilate 3,4-dioxygenase activity

8 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

3-hydroxyanthranilate 3,4-dioxygenase activity

IBA

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

pyridine nucleotide biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

response to cadmium ion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

neuron cellular homeostasis

1 reference

8 April 2019

3-Hydroxyanthranilate oxygenase activity is increased in the brains of Huntington disease victims

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

1 reference

8 April 2019

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

tryptophan catabolic process

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

TAS

electron transport chain

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

quinolinate biosynthetic process

3 references

27 March 2018

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

27 March 2018

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

27 March 2018

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

quinolinate biosynthetic process

4 references

8 April 2019

Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

8 April 2019

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

'de novo' NAD biosynthetic process from tryptophan

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46952&geneProductId=UniProtKB:P46952

anthranilate metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952

quinolinate metabolic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46952