Myotubularin 1 (Q22676738)

Protein-tyrosine phosphatase-like

1 reference

PH-like domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Tyrosine specific protein phosphatases domain, protein family

1 reference

Myotubularin-like phosphatase domain, protein family

1 reference

GRAM domain, protein family

1 reference

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

Protein-tyrosine phosphatase, active site, protein family

1 reference

intermediate filament binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

4 references

8 April 2019

A phosphoinositide conversion mechanism for exit from endosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

phosphatidylinositol binding

IPI

1 reference

8 April 2019

Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

protein tyrosine phosphatase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

phosphatidylinositol-3-phosphatase activity

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

1 January 2018

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

1 January 2018

Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13496&geneProductId=UniProtKB:Q13496

phosphatidylinositol-3-phosphatase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

The PtdIns3P phosphatase myotubularin is a cytoplasmic protein that also localizes to Rac1-inducible plasma membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

The PtdIns3P phosphatase myotubularin is a cytoplasmic protein that also localizes to Rac1-inducible plasma membrane ruffles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

negative regulation of autophagosome assembly

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

negative regulation of protein kinase B signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

protein dephosphorylation

1 reference

8 April 2019

Association of SET domain and myotubularin-related proteins modulates growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

negative regulation of TOR signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

mitochondrion distribution

3 references

8 April 2019

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

negative regulation of proteasomal ubiquitin-dependent protein catabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

phosphatidylinositol biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

peptidyl-tyrosine dephosphorylation

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

positive regulation of skeletal muscle tissue growth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

phosphatidylinositol dephosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

8 April 2019

Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13496

1 reference

Tyrosine specific protein phosphatases domain

1 reference

Protein-tyrosine phosphatase, active site

1 reference

Myotubularin-like phosphatase domain

1 reference

Protein-tyrosine phosphatase, catalytic

1 reference