FTO Obesity Variant Circuitry and Adipocyte Browning in Humans (Q22305008)

regulation of brown fat cell differentiation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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19

Manolis Kellis

Manolis

Kellis

1 reference

7 February 2023

Wouter Meuleman

5

Wouter

Meuleman

1 reference

7 February 2023

15

Daniel J. Drucker

Daniel J

Drucker

1 reference

7 February 2023

16

Gunnar Mellgren

Gunnar

Mellgren

1 reference

7 February 2023

2

Simon N. Dankel

Simon N

Dankel

1 reference

7 February 2023

1

Melina Claussnitzer

Melina

Claussnitzer

1 reference

7 February 2023

7

Viktoria Glunk

Viktoria

Glunk

1 reference

7 February 2023

18

Hans

Hauner

Hans Hauner

1 reference

7 February 2023

Kyoung-Han Kim

3

Kyoung-Han

Kim

1 reference

7 February 2023

Gerald Quon

4

Gerald

Quon

1 reference

7 February 2023

Christine Haugen

6

Christine

Haugen

1 reference

7 February 2023

Isabel S. Sousa

8

Isabel S

Sousa

1 reference

7 February 2023

Jacqueline L. Beaudry

9

Jacqueline L

Beaudry

1 reference

7 February 2023

Vijitha Puviindran

10

Vijitha

Puviindran

1 reference

7 February 2023

Nezar A. Abdennur

11

Nezar A

Abdennur

1 reference

7 February 2023

Jannel Liu

12

Jannel

Liu

1 reference

7 February 2023

Per-Arne Svensson

13

Per-Arne

Svensson

1 reference

7 February 2023

Yi-Hsiang Hsu

14

Yi-Hsiang

Hsu

1 reference

7 February 2023

Chi-Chung Hui

17

Chi-Chung

Hui

1 reference

The New England Journal of Medicine

7 February 2023

language of work or name

English

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publication date

3 September 2015

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published in

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volume

373

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issue

10

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page(s)

895-907

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cites work

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The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

19 March 2017

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The bigger picture of FTO: the first GWAS-identified obesity gene

19 March 2017

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Genome engineering using the CRISPR-Cas9 system

19 March 2017

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Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3

19 March 2017

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Identification and importance of brown adipose tissue in adult humans

19 March 2017

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Common variants near MC4R are associated with fat mass, weight and risk of obesity

19 March 2017

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

19 March 2017

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The novel Mrf-2 DNA-binding domain recognizes a five-base core sequence through major and minor-groove contacts

19 March 2017

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Obesity-associated variants within FTO form long-range functional connections with IRX3

19 March 2017

1 reference

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

19 March 2017

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Inactivation of the Fto gene protects from obesity

19 March 2017

1 reference

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Variation in FTO contributes to childhood obesity and severe adult obesity

19 March 2017

1 reference

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IRF4 is a key thermogenic transcriptional partner of PGC-1α

19 March 2017

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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

19 March 2017

1 reference

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Functional brown adipose tissue in healthy adults

7 April 2017

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Cold-activated brown adipose tissue in healthy men

7 April 2017

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Integrative analysis of 111 reference human epigenomes

7 April 2017

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Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

7 April 2017

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Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice

7 April 2017

1 reference

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Brown adipose tissue and its therapeutic potential.

27 September 2017

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Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

27 September 2017

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Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.

27 September 2017

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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

27 September 2017

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Genetic variation at the FTO locus influences RBL2 gene expression

27 September 2017

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Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue

27 September 2017

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Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old.

27 September 2017

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Large-scale imputation of epigenomic datasets for systematic annotation of diverse human tissues

27 September 2017

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Modulator recognition factor-2 regulates triglyceride metabolism in adipocytes

27 September 2017

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UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic.

30 May 2018

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Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

29 November 2018

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29 November 2018

Identifiers

DOI

10.1056/NEJMOA1502214

1 reference

release_7iokpii3jngvfk57nl5vwsabxa

Fatcat ID

0 references

1 reference

1 reference

1 reference