The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho (Q22254081)

GOA release 2020-03-11

TSC complex subunit 1

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GOA release 2020-03-11

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R F Lamb

1

Richard F.

Lamb

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7 February 2023

C Roy

2

Christian

Roy

1 reference

7 February 2023

T J Diefenbach

3

Tom J.

Diefenbach

1 reference

7 February 2023

H V Vinters

4

Harry V.

Vinters

1 reference

7 February 2023

M W Johnson

5

Michael W.

Johnson

1 reference

7 February 2023

D G Jay

6

Daniel G.

Jay

1 reference

7 February 2023

A Hall

7

Alan

Hall

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Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

7 February 2023

publication date

May 2000

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language of work or name

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2

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issue

5

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page(s)

281-7

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cites work

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Identification and characterization of the tuberous sclerosis gene on chromosome 16

21 January 2018

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Linkage of an important gene locus for tuberous sclerosis to a chromosome 16 marker for polycystic kidney disease

21 January 2018

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Two loci for tuberous sclerosis: one on 9q34 and one on 16p13.

21 January 2018

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gigas, a Drosophila homolog of tuberous sclerosis gene product-2, regulates the cell cycle

21 January 2018

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Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region

21 January 2018

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Molecular Genetic and Phenotypic Analysis Reveals Differences between TSC1 and TSC2 Associated Familial and Sporadic Tuberous Sclerosis

21 January 2018

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Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

21 January 2018

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Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

21 January 2018

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Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

21 January 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

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Rho- and Rac-dependent Assembly of Focal Adhesion Complexes and Actin Filaments in Permeabilized Fibroblasts: An Essential Role for Ezrin/Radixin/Moesin Proteins

21 January 2018

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Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

21 January 2018

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Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl

21 January 2018

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A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

21 January 2018

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Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members

21 January 2018

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Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts

21 January 2018

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Ultrastructural localization of ras-related proteins using epitope-tagged plasmids

21 January 2018

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Yeast two-hybrid system to detect protein-protein interactions with Rho GTPases

21 January 2018

1 reference

The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane

21 January 2018

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Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

21 January 2018

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Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family

21 January 2018

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Chromophore-assisted laser inactivation (CALI): probing protein function in situ with a high degree of spatial and temporal resolution

21 January 2018

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

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Regulation of cortical structure by the ezrin-radixin-moesin protein family

21 January 2018

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Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα 13

21 January 2018

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Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression

21 January 2018

1 reference

21 January 2018

Integrins and anoikis

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Cell-adhesion-dependent influences on genomic instability and carcinogenesis

21 January 2018

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Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

21 January 2018

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Impairment of cell adhesion by expression of the mutant neurofibromatosis type 2 (NF2) genes which lack exons in the ERM-homology domain

21 January 2018

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E-cadherin germline mutations in familial gastric cancer.

21 January 2018

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Purification of recombinant Rho/Rac/G25K from Escherichia coli

21 January 2018

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Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

21 January 2018

1 reference

A Dual Involvement of the Amino-terminal Domain of Ezrin in F- and G-actin Binding

21 January 2018

1 reference

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

Protein Kinase C-θ Phosphorylation of Moesin in the Actin-binding Sequence

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/35010550

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