The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium (Q22011092)

7 February 2023

C Fernandez-Catalan

2

C

Fernandez-Catalan

1 reference

7 February 2023

M Braun

3

M

Braun

1 reference

7 February 2023

R Huber

4

R

Huber

1 reference

7 February 2023

H Masumoto

5

H

Masumoto

1 reference

7 February 2023

K Nakagawa

6

K

Nakagawa

1 reference

7 February 2023

A Irie

7

A

Irie

1 reference

7 February 2023

H Sorimachi

8

H

Sorimachi

1 reference

7 February 2023

G Bourenkow

9

G

Bourenkow

1 reference

7 February 2023

H Bartunik

10

H

Bartunik

1 reference

7 February 2023

K Suzuki

11

K

Suzuki

1 reference

7 February 2023

W Bode

12

W

Bode

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 February 2023

language of work or name

English

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publication date

18 January 2000

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published in

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volume

97

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issue

2

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page(s)

588-92

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cites work

Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A

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Structure and physiological function of calpains

19 March 2017

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An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective

19 March 2017

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Nucleotide sequence of a cDNA coding for the small subunit of human calcium-dependent protease

19 March 2017

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Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change?

19 March 2017

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Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding

19 March 2017

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Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes

19 March 2017

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Structure of papain refined at 1.65 A resolution

19 March 2017

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The CCP4 suite: programs for protein crystallography

19 March 2017

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ALSCRIPT: a tool to format multiple sequence alignments

19 March 2017

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SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

19 March 2017

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Calcium-binding properties of human erythrocyte calpain

19 March 2017

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Calpain: novel family members, activation, and physiologic function

19 March 2017

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C2-domains, structure and function of a universal Ca2+-binding domain

19 March 2017

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Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease

7 April 2017

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Characterization of cDNA clones encoding a novel calcium-activated neutral proteinase from Schistosoma mansoni

12 September 2017

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Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex

12 September 2017

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Is calpain activity regulated by membranes and autolysis or by calcium and calpastatin?

12 September 2017

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Calpainopathy-a survey of mutations and polymorphisms

12 September 2017

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Calpains: intact and active?

30 May 2018

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Functional properties of recombinant calpain I and of mutants lacking domains III and IV of the catalytic subunit

30 May 2018

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Preference of calcium‐dependent interactions between calmodulin‐like domains of calpain and calpastatin subdomains

30 May 2018

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Structure of tumour necrosis factor

30 May 2018

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Calpain: a protease in search of a function?

30 May 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.2.588

Crystallization and preliminary X-ray characterization of VanA from Enterococcus faecium BM4147: towards the molecular basis of bacterial resistance to the glycopeptide antibiotic vancomycin.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.2.588

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.2.588

Crystallization and X-ray crystallographic analysis of m-calpain, a Ca2+-dependent protease

21 January 2018

1 reference

12 December 2020

Positive regulation of mu-calpain action by polyphosphoinositides

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

A catalytic subunit of calpain possesses full proteolytic activity

1 reference

12 December 2020

Structural modifications associated with the change in Ca2+ sensitivity on activation of m-calpain

1 reference

12 December 2020

1 reference

12 December 2020

Overexpression, purification, and characterization of human m-calpain and its active site mutant, m-C105S-calpain, using a baculovirus expression system

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.97.2.588

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