RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency (Q22009001)

transcription coregulator activity

GOA release 2020-03-11

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GOA release 2020-03-11

Bare lymphocyte syndrome

1 reference

U M Nagarajan

1

U M

Nagarajan

1 reference

7 February 2023

P Louis-Plence

2

P

Louis-Plence

1 reference

7 February 2023

A DeSandro

3

A

DeSandro

1 reference

7 February 2023

R Nilsen

4

R

Nilsen

1 reference

7 February 2023

A Bushey

5

A

Bushey

1 reference

7 February 2023

J M Boss

6

J M

The NF-kappa B and I kappa B proteins: new discoveries and insights

Boss

1 reference

7 February 2023

language of work or name

English

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publication date

February 1999

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published in

Immunity

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volume

10

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page(s)

153-62

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issue

2

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Regulation of transcription of MHC class II genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Major histocompatibility complex class II deficiency: a clinical review

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Mutation and Modeling Analysis of theSaccharomyces cerevisiaeSwi6 Ankyrin Repeats†

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Two B cell factors bind the HLA-DRA X box region and recognize different subsets of HLA class II promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Two complementation groups account for most cases of inherited MHC class II deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

A new class of yeast transcriptional activators

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

MHC class II-deficient combined immunodeficiency: a disease of gene regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Regulation of MHC class II genes: lessons from a disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Induction of MHC class I expression by the MHC class II transactivator CIITA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

TNF regulates the in vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

GAL4-VP16 is an unusually potent transcriptional activator

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Specific complex formation between the type II bare lymphocyte syndrome-associated transactivators CIITA and RFX5

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Conserved upstream sequences of human class II major histocompatibility genes enhance expression of class II genes in wild-type but not mutant B-cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Cloning of cDNAs for Fanconi's anaemia by functional complementation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021

Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980016-3

7 January 2021