Dickkopf WNT signaling pathway inhibitor 1 (Q21984422)

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mammalian protein found in Mus musculus
  • dickkopf homolog 1
  • Dkk1
  • dickkopf-related protein 1
  • dickkopf-like protein 1
  • dickkopf-1
  • dkk-1
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Language Label Description Also known as
English
Dickkopf WNT signaling pathway inhibitor 1
mammalian protein found in Mus musculus
  • dickkopf homolog 1
  • Dkk1
  • dickkopf-related protein 1
  • dickkopf-like protein 1
  • dickkopf-1
  • dkk-1

Statements

molecular function
cell component
biological process
negative regulation of Wnt signaling pathway
determination method
IDA
IEA
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IEA
retrieved
14 February 2019
stated in
Wnt signaling mediates regional specification in the vertebrate face
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Macrophage Wnt7b is critical for kidney repair and regeneration
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
negative regulation of canonical Wnt signaling pathway
determination method
IDA
IGI
IEA
IMP
ISO
12 references
retrieved
31 January 2017
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
ISO
retrieved
31 January 2017
stated in
Dkk1 and Wnt3 interact to control head morphogenesis in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IMP
retrieved
31 January 2017
stated in
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IGI
retrieved
31 January 2017
stated in
Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IGI
retrieved
31 January 2017
stated in
Dkk1 and Wnt3 interact to control head morphogenesis in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IGI
retrieved
31 January 2017
stated in
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IGI
retrieved
31 January 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IEA
retrieved
31 January 2017
stated in
Deficient Wnt signalling triggers striatal synaptic degeneration and impaired motor behaviour in adult mice
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IDA
retrieved
31 January 2017
stated in
Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IDA
retrieved
31 January 2017
stated in
Wnt-beta-catenin signaling initiates taste papilla development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IDA
retrieved
31 January 2017
stated in
Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IDA
retrieved
31 January 2017
stated in
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O54908
determination method
IDA
negative regulation of canonical Wnt signaling pathway
determination method
IBA
IDA
IEA
IGI
IMP
ISO
14 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
ISO
retrieved
14 February 2019
stated in
Dkk1 and Wnt3 interact to control head morphogenesis in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IMP
retrieved
14 February 2019
stated in
Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IGI
retrieved
14 February 2019
stated in
Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IGI
retrieved
14 February 2019
stated in
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IGI
retrieved
14 February 2019
stated in
Dkk1 and Wnt3 interact to control head morphogenesis in the mouse
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IGI
retrieved
14 February 2019
stated in
Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IEA
retrieved
14 February 2019
stated in
Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Deficient Wnt signalling triggers striatal synaptic degeneration and impaired motor behaviour in adult mice
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Wnt-beta-catenin signaling initiates taste papilla development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Ectodomains of the LDL receptor-related proteins LRP1b and LRP4 have anchorage independent functions in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IDA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O54908
determination method
IBA

Identifiers

 
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