Necdin, MAGE family member (Q21984208)

http://www.ebi.ac.uk/interpro/protein/P25233

MAGE homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

DNA-binding transcription activator activity, RNA polymerase II-specific

IEA

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IDA

1 reference

14 February 2019

The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

6 references

14 February 2019

The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

The Prader-Willi syndrome protein necdin interacts with the E1A-like inhibitor of differentiation EID-1 and promotes myoblast differentiation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth

IPI

gamma-tubulin binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Cellular and subcellular localization of necdin in fetal and adult mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

3 references

3 references

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

Cellular and subcellular localization of necdin in fetal and adult mouse brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

14 February 2019

The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

respiratory system process

IDA

biological process

1 reference

14 February 2019

Disruption of the mouse necdin gene results in early post-natal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Disruption of the mouse necdin gene results in early post-natal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

neurotrophin TRK receptor signaling pathway

1 reference

14 February 2019

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

multicellular organismal homeostasis

1 reference

14 February 2019

Disruption of the mouse necdin gene results in early post-natal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

post-embryonic development

1 reference

14 February 2019

Disruption of the mouse necdin gene results in early post-natal lethality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25233&geneProductId=UniProtKB:P25233

respiratory gaseous exchange by respiratory system

IEA

1 reference

14 February 2019

Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

central nervous system development

1 reference

14 February 2019

Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

sensory perception of pain

1 reference

14 February 2019

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

negative regulation of cell population proliferation

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

14 February 2019

Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

transcription by RNA polymerase II

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25233&geneProductId=UniProtKB:P25233

regulation of transcription, DNA-templated

IEA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25233

1 reference

InterPro Release 71.0