Spen family transcription repressor (Q21982612)

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mammalian protein found in Mus musculus

Msx2 interacting nuclear target protein
SMART/HDAC1-associated repressor protein
Spen
msx2-interacting protein
SPEN homolog, transcriptional regulator
SPEN homolog

Language	Label	Description	Also known as
English	Spen family transcription repressor	mammalian protein found in Mus musculus	Msx2 interacting nuclear target protein SMART/HDAC1-associated repressor protein Spen msx2-interacting protein SPEN homolog, transcriptional regulator SPEN homolog

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

SPOC-like, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

Spen paralogue and orthologue SPOC, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SHARP, RNA recognition motif 3, protein family

1 reference

based on heuristic

inferred from protein domain or family

SHARP, RNA recognition motif 4, protein family

1 reference

based on heuristic

inferred from protein domain or family

Spen paralogue/orthologue C-terminal, metazoa, protein family

1 reference

based on heuristic

inferred from protein domain or family

SHARP, RNA recognition motif 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

SHARP, RNA recognition motif 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

RNA recognition motif domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

14 February 2019

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

transcription corepressor activity

determination method

1 reference

10 September 2018

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

single-stranded DNA binding

determination method

1 reference

14 February 2019

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

nucleic acid binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

transcription repressor complex

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

determination method

3 references

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

31 January 2018

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

31 January 2018

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

14 February 2019

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

14 February 2019

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

biological process

Notch signaling pathway

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

mRNA splicing, via spliceosome

determination method

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

regulation of transcription, DNA-templated

determination method

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

transcription, DNA-templated

determination method

1 reference

31 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q62504&geneProductId=UniProtKB:Q62504

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

positive regulation of neurogenesis

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

negative regulation of transcription, DNA-templated

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

14 February 2019

Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

14 February 2019

The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62504

determination method

Spen paralogue/orthologue C-terminal, metazoa

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

Spen paralogue and orthologue SPOC, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

RNA recognition motif domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

SHARP, RNA recognition motif 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

SHARP, RNA recognition motif 3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

SHARP, RNA recognition motif 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

SHARP, RNA recognition motif 4

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q62504

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000077925

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000077925

ENSMUSP00000101412

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000101412

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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