Metal response element binding transcription factor 2 (Q21981798)

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mammalian protein found in Mus musculus

zinc-regulated factor 1
ziRF1
metal regulatory transcription factor 2
mPCl2
metal-response element-binding transcription factor 2
Metal-response element DNA-binding protein M96
Mtf2
polycomb-like protein 2
metal response element DNA-binding protein M96

Language	Label	Description	Also known as
English	Metal response element binding transcription factor 2	mammalian protein found in Mus musculus	zinc-regulated factor 1 ziRF1 metal regulatory transcription factor 2 mPCl2 metal-response element-binding transcription factor 2 Metal-response element DNA-binding protein M96 Mtf2 polycomb-like protein 2 metal response element DNA-binding protein M96

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Zinc finger, FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

Zinc finger, RING/FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

Polycomb-like MTF2 factor 2, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tudor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-finger, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, PHD-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

methylated histone binding

determination method

3 references

27 February 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02395&geneProductId=UniProtKB:Q02395

determination method

27 February 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02395&geneProductId=UniProtKB:Q02395

determination method

27 February 2018

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02395&geneProductId=UniProtKB:Q02395

determination method

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

protein binding

determination method

1 reference

14 February 2019

Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

RNA polymerase II transcription regulatory region sequence-specific DNA binding

determination method

1 reference

14 February 2019

Isolation of a cDNA encoding a metal response element binding protein using a novel expression cloning procedure: the one hybrid system

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

1 reference

14 February 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

DNA-binding transcription factor activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

nucleosome binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

methylated histone binding

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

sequence-specific DNA binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

determination method

3 references

ESC/E(Z) complex

determination method

1 reference

27 February 2018

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02395&geneProductId=UniProtKB:Q02395

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

ESC/E(Z) complex

determination method

biological process

stem cell population maintenance

determination method

1 reference

14 February 2019

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

positive regulation of histone H3-K27 methylation

determination method

2 references

27 February 2018

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02395&geneProductId=UniProtKB:Q02395

determination method

27 February 2018

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02395&geneProductId=UniProtKB:Q02395

determination method

negative regulation of histone H3-K27 methylation

determination method

1 reference

14 February 2019

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

negative regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

segment specification

determination method

1 reference

14 February 2019

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

stem cell differentiation

determination method

1 reference

14 February 2019

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

cellular response to leukemia inhibitory factor

determination method

1 reference

14 February 2019

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

chromatin organization

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

positive regulation of histone H3-K27 methylation

determination method

3 references

14 February 2019

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02395

determination method

Polycomb-like MTF2 factor 2, C-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

Zinc finger, PHD-type, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

Zinc finger, PHD-finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

Zinc finger, PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02395

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000137843

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000137843

ENSMUSP00000132596

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000132596

ENSMUSP00000121697

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000121697

ENSMUSP00000080278

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000080278

ENSMUSP00000128797

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000128797

ENSMUSP00000130536

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000130536

ENSMUSP00000108245

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000108245

ENSMUSP00000126452

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126452

ENSMUSP00000126297

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000126297

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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