Inhibitor of DNA binding 3 (Q21981658)

http://www.ebi.ac.uk/interpro/protein/P41133

Helix-loop-helix DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P41133

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

protein dimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

1 reference

14 February 2019

The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

protein domain specific binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

DNA-binding transcription factor activity

1 reference

24 April 2018

Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

transcription factor binding

1 reference

24 April 2018

E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

5 references

14 February 2019

E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Physical and functional interactions between the transcriptional inhibitors Id3 and ITF-2b. Evidence toward a novel mechanism regulating muscle-specific gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Acheron, an novel LA antigen family member, binds to CASK and forms a complex with Id transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

DNA-binding transcription factor activity

IPI

transcription factor binding

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

Helix-loop-helix proteins in Schwann cells: a study of regulation and subcellular localization of Ids, REB, and E12/47 during embryonic and postnatal development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Helix-loop-helix proteins in Schwann cells: a study of regulation and subcellular localization of Ids, REB, and E12/47 during embryonic and postnatal development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

negative regulation of myoblast differentiation

biological process

1 reference

14 February 2019

Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

regulation of transcription, DNA-templated

IMP

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

epithelial cell differentiation

1 reference

14 February 2019

Inhibitors of differentiation and DNA binding (Ids) regulate Math1 and hair cell formation during the development of the organ of Corti

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

muscle organ development

1 reference

14 February 2019

Expression of the helix-loop-helix gene Id3 during murine embryonic development

notochord development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

negative regulation of gene expression

1 reference

14 February 2019

The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

negative regulation of osteoblast differentiation

1 reference

14 February 2019

Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

1 reference

14 February 2019

Expression of the helix-loop-helix gene Id3 during murine embryonic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

multicellular organism development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

1 reference

14 February 2019

Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

central nervous system development

IGI

1 reference

14 February 2019

Expression of the helix-loop-helix gene Id3 during murine embryonic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

1 reference

24 April 2018

A role for Id2 in regulating photic entrainment of the mammalian circadian system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

neuron differentiation

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41133&geneProductId=UniProtKB:P41133

Expression of the helix-loop-helix gene Id3 during murine embryonic development

metanephros development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

negative regulation of transcription, DNA-templated

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

14 February 2019

A role for Id2 in regulating photic entrainment of the mammalian circadian system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

cellular response to leptomycin B

1 reference

14 February 2019

The metalloid arsenite induces nuclear export of Id3 possibly via binding to the N-terminal cysteine residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

transcription, DNA-templated

1 reference

14 February 2019

Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

negative regulation of DNA binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

negative regulation of neuron differentiation

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41133

Myc-type, basic helix-loop-helix (bHLH) domain

regulation of cell cycle

3 references

1 reference

stated in

InterPro Release 71.0