Structure, function, aging and turnover of aggrecan in the intervertebral disc (Q21564048)

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Human intervertebral disc aggrecan inhibits nerve growth in vitro

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

A synthetic peptide of link protein stimulates the biosynthesis of collagens II, IX and proteoglycan by cells of the intervertebral disc

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Structure of chondroitin sulfate on aggrecan isolated from bovine tibial and costochondral growth plates

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Calcification in human intervertebral disc degeneration and scoliosis

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Biomimetic aggrecan reduces cartilage extracellular matrix from degradation and lowers catabolic activity in ex vivo and in vivo models.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Complete coding sequence of bovine aggrecan: comparative structural analysis

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Isoaspartate formation and neurodegeneration in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Complete coding sequence, deduced primary structure, chromosomal localization, and structural analysis of murine aggrecan

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

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7 January 2021

Aspartic acid racemisation in purified elastin from arteries as basis for age estimation

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

The structure and degradation of aggrecan in human intervertebral disc

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Biological repair of the degenerated intervertebral disc by the injection of growth factors

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

On the accumulation of d-aspartate in elastin and other proteins of the ageing aorta

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Non-enzymatic, post-translational, amino acid modifications in ageing. A brief review

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

In vivo racemization in mammalian proteins

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7 January 2021

O-Linked oligosaccharides of human articular cartilage proteoglycan

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7 January 2021

Studies on the interaction of newly secreted proteoglycan subunits with hyaluronate in human articular cartilage

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7 January 2021

Senescence and the accumulation of abnormal proteins

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Length variation in the keratan sulfate domain of mammalian aggrecan

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7 January 2021

Synthesis and characterization of an aggrecan mimic

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7 January 2021

Incorporation of an aggrecan mimic prevents proteolytic degradation of anisotropic cartilage analogs

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7 January 2021

Injectable hydrogels with high fixed charge density and swelling pressure for nucleus pulposus repair: biomimetic glycosaminoglycan analogues.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

A recessive skeletal dysplasia, SEMD aggrecan type, results from a missense mutation affecting the C-type lectin domain of aggrecan

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Longevity of elastin in human intervertebral disc as probed by the racemization of aspartic acid

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

The many ways to cleave hyaluronan.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Link protein can retard the degradation of hyaluronan in proteoglycan aggregates.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Enhanced levels of non-enzymatic glycation and pentosidine crosslinking in spontaneous osteoarthritis progression.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein

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7 January 2021

The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus

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7 January 2021

The molecular basis of intervertebral disc degeneration

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7 January 2021

Genetic polymorphisms associated with intervertebral disc degeneration.

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7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Hyal2--less active, but more versatile?

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7 January 2021

Characterization of human aggrecanase 2 (ADAM-TS5): substrate specificity studies and comparison with aggrecanase 1 (ADAM-TS4).

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aspartic acid racemisation in dentine as a measure of ageing

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aspartic acid racemisation in the human lens during ageing and in cataract formation

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Isolation of the N-terminal globular protein domains from cartilage proteoglycans. Identification of G2 domain and its lack of interaction with hyaluronate and link protein

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Proteoglycans isolated from dissociative extracts of differently aged human articular cartilage: characterization of naturally occurring hyaluronan-binding fragments of aggrecan

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7 January 2021

Aggrecan degradation in human intervertebral disc and articular cartilage

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Proteoglycan structure and metabolism during maturation and ageing of human articular cartilage

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Prediction of protein deamidation rates from primary and three-dimensional structure

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aspartic acid racemization in tooth enamel from living humans

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aspartic acid racemization in heavy molecular weight crystallins and water insoluble protein from normal human lenses and cataracts

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

1 reference

7 January 2021

N- and O-linked keratan sulfate on the hyaluronan binding region of aggrecan from mature and immature bovine cartilage

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Undersulfation of proteoglycans synthesized by chondrocytes from a patient with achondrogenesis type 1B homozygous for an L483P substitution in the diastrophic dysplasia sulfate transporter.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

A human-specific polymorphism in the coding region of the aggrecan gene. Variable number of tandem repeats produce a range of core protein sizes in the general population.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Identification of hyaluronan-binding domains of aggrecan

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aggrecan synthesis and secretion. A paradigm for molecular and cellular coordination of multiglobular protein folding and intracellular trafficking

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Sulfation of chondroitin sulfate in human articular cartilage. The effect of age, topographical position, and zone of cartilage on tissue composition

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Effect of collagen turnover on the accumulation of advanced glycation end products

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aspartic acid racemization and collagen degradation markers reveal an accumulation of damage in tendon collagen that is enhanced with aging

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Link protein N-terminal peptide binds to bone morphogenetic protein (BMP) type II receptor and drives matrix protein expression in rabbit intervertebral disc cells

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

The glycosaminoglycan attachment regions of human aggrecan

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Collagen turnover in normal and degenerate human intervertebral discs as determined by the racemization of aspartic acid

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

A mutation in the variable repeat region of the aggrecan gene (AGC1) causes a form of spondyloepiphyseal dysplasia associated with severe, premature osteoarthritis

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Roles of aggrecan, a large chondroitin sulfate proteoglycan, in cartilage structure and function.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Changes in collagen cross-linking in degenerative disc disease and scoliosis

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Association between an aggrecan gene polymorphism and lumbar disc degeneration

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Human intervertebral disc aggrecan inhibits endothelial cell adhesion and cell migration in vitro

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

What is intervertebral disc degeneration, and what causes it?

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Aspartic acid racemization: evidence for marked longevity of elastin in human skin.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Intervertebral disc, sensory nerves and neurotrophins: who is who in discogenic pain?

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Intervertebral disc: anatomy-physiology-pathophysiology-treatment

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Protein synthesis, posttranslational modifications, and aging

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Studies on the G3 Domain of Aggrecan from Human Cartilagea

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

1 reference

7 January 2021

Accumulation of D-aspartic acid with age in the human brain.

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Considerations on the role of aspartic acid racemization in the aging process

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Racemization of Amino Acids in Nature

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Short stature, accelerated bone maturation, and early growth cessation due to heterozygous aggrecan mutations

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Best paper NASS 2013: link-N can stimulate proteoglycan synthesis in the degenerated human intervertebral discs

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021

Biochemical changes in the collagen of human osteoporotic bone matrix

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https://api.crossref.org/works/10.1016%2FJ.BBAGEN.2014.07.013

7 January 2021