Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria (Q21563375)

GOA release 2020-03-11

1 reference

4

Wendou Yu

Wendou

Yu

1 reference

2 September 2022

12

Nobutaka Hattori

Nobutaka

Hattori

1 reference

2 September 2022

Song Liu

1

Song

Liu

1 reference

2 September 2022

Tomoyo Sawada

2

Tomoyo

Sawada

1 reference

2 September 2022

Seongsoo Lee

3

Seongsoo

Lee

1 reference

2 September 2022

George Silverio

5

George

Silverio

1 reference

2 September 2022

Philomena Alapatt

6

Philomena

Alapatt

1 reference

2 September 2022

Ivan Millan

7

Ivan

Millan

1 reference

2 September 2022

Alice Shen

8

Alice

Shen

1 reference

2 September 2022

William Saxton

9

William

Saxton

1 reference

2 September 2022

Tomoko Kanao

10

Tomoko

Kanao

1 reference

2 September 2022

Ryosuke Takahashi

11

Ryosuke

Takahashi

1 reference

2 September 2022

Yuzuru Imai

13

Yuzuru

Imai

1 reference

2 September 2022

Bingwei Lu

14

Bingwei

Creative Commons Attribution 4.0 International

Lu

1 reference

2 September 2022

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS Genetics

0 references

volume

8

0 references

page(s)

e1002537

0 references

issue

3

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copyright license

start time

1 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

1 reference

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Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

19 March 2017

1 reference

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

19 March 2017

1 reference

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

19 March 2017

1 reference

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

19 March 2017

1 reference

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PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

19 March 2017

1 reference

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PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

19 March 2017

1 reference

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

19 March 2017

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Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis

19 March 2017

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

19 March 2017

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Chromosome 6-linked autosomal recessive early-onset Parkinsonism: linkage in European and Algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family. The French Parkinson's Disease Genetics Study

19 March 2017

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

19 March 2017

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Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder

19 March 2017

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Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

19 March 2017

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Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

19 March 2017

1 reference

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

19 March 2017

1 reference

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

7 April 2017

1 reference

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

7 April 2017

1 reference

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The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

7 April 2017

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The PINK1/Parkin pathway regulates mitochondrial morphology

7 April 2017

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Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

7 April 2017

1 reference

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

7 April 2017

1 reference

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Kinesin and dynein superfamily proteins and the mechanism of organelle transport

7 April 2017

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Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

7 April 2017

1 reference

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Genetic mutations and mitochondrial toxins shed new light on the pathogenesis of Parkinson's disease

7 April 2017

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Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

12 September 2017

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Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

12 September 2017

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The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

12 September 2017

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The parkinsonian mimetic, MPP+, specifically impairs mitochondrial transport in dopamine axons

12 September 2017

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12 September 2017

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Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice

12 September 2017

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The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

12 September 2017

1 reference

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12 September 2017

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12 September 2017

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12 September 2017

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Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons

12 September 2017

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The axonal transport of mitochondria.

12 September 2017

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Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

12 September 2017

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PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons

30 May 2018

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30 May 2018

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21 January 2018

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Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport.

21 January 2018

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21 January 2018

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1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22396657

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002537

1 reference

1644787

1644787

1 reference

1 reference

1 reference