ATPase, Ca++ transporting, plasma membrane 2 (Q21499093)

HAD-like superfamily

1 reference

Plasma membrane calcium-transporting ATPase 2

1 reference

P-type ATPase, transmembrane domain superfamily

1 reference

P-type ATPase, cytoplasmic domain N

1 reference

HAD superfamily

1 reference

Cation-transporting P-type ATPase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Plasma membrane calcium transporting P-type ATPase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Cation-transporting P-type ATPase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

calcium-dependent ATPase activity

1 reference

14 February 2019

The calcium-sensing receptor regulates plasma membrane calcium adenosine triphosphatase isoform 2 activity in mammary epithelial cells: a mechanism for calcium-regulated calcium transport into milk

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0K7&geneProductId=UniProtKB:Q9R0K7

P-type calcium transporter activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

2 references

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

protein C-terminus binding

2 references

3 references

acetylcholine receptor binding

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0K7&geneProductId=UniProtKB:Q9R0K7

glutamate receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

integral component of membrane

cell component

2 references

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

A point mutation in a plasma membrane Ca(2+)-ATPase gene causes deafness in Wriggle Mouse Sagami

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

endoplasmic reticulum

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

2 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

neuronal cell body membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

postsynaptic density membrane

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0K7&geneProductId=UniProtKB:Q9R0K7

parallel fiber to Purkinje cell synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

glutamatergic synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

integral component of postsynaptic membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

integral component of presynaptic active zone membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

integral component of postsynaptic density membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

PMCA2 mutation causes structural changes in the auditory system in deafwaddler mice

biological process

regulation of cell size

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

5 references

14 February 2019

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Fundamental study on ataxic mice (wriggle mouse Sagami)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Cerebellar nitric oxide synthase, cGMP and motor function in two lines of cerebellar mutant mice, Staggerer and Wriggle Mouse Sagami

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A neurochemical study of a new mutant mouse presenting myoclonus-like involuntary movement: a possible model of spontaneous serotonergic hyperactivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

neuromuscular process controlling balance

3 references

14 February 2019

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Haplo-insufficiency revealed in deafwaddler mice when tested for hearing loss and ataxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

Abnormal synaptic architecture in the cerebellar cortex of a new dystonic mutant mouse, Wriggle Mouse Sagami

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

cerebellar Purkinje cell differentiation

1 reference

14 February 2019

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

cellular calcium ion homeostasis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

serotonin metabolic process

1 reference

14 February 2019

A neurochemical study of a new mutant mouse presenting myoclonus-like involuntary movement: a possible model of spontaneous serotonergic hyperactivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

PMCA2 mutation causes structural changes in the auditory system in deafwaddler mice

organelle organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

A novel mutant mouse, joggle, with inherited ataxia

cerebellum development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

regulation of synaptic plasticity

1 reference

14 February 2019

Plasma membrane Ca2+ ATPase 2 contributes to short-term synapse plasticity at the parallel fiber to Purkinje neuron synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

detection of mechanical stimulus involved in sensory perception of sound

1 reference

14 February 2019

Multisensory plasticity in congenitally deaf mice: how are cortical areas functionally specified?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

auditory receptor cell stereocilium organization

1 reference

14 February 2019

PMCA2 mutation causes structural changes in the auditory system in deafwaddler mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

cerebellar Purkinje cell layer morphogenesis

1 reference

14 February 2019

Plasma membrane Ca2+ ATPase 2 contributes to short-term synapse plasticity at the parallel fiber to Purkinje neuron synapse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

inner ear morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

A novel mutant mouse, joggle, with inherited ataxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

A point mutation in a plasma membrane Ca(2+)-ATPase gene causes deafness in Wriggle Mouse Sagami

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

PMCA2 mutation causes structural changes in the auditory system in deafwaddler mice

inner ear development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

inner ear receptor cell differentiation

1 reference

14 February 2019

PMCA2 mutation causes structural changes in the auditory system in deafwaddler mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

1 reference

14 February 2019

Null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2 impairs calcium transport into milk

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

otolith mineralization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

calcium ion transport

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2 impairs calcium transport into milk

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

cerebellar granule cell differentiation

1 reference

14 February 2019

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

positive regulation of calcium ion transport

1 reference

14 February 2019

The calcium-sensing receptor regulates plasma membrane calcium adenosine triphosphatase isoform 2 activity in mammary epithelial cells: a mechanism for calcium-regulated calcium transport into milk

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

calcium ion transmembrane transport

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

11 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Haplo-insufficiency revealed in deafwaddler mice when tested for hearing loss and ataxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Evaluation of inner ear histology and auditory brainstem response in Wriggle Mouse Sagami

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

IGI

neuron differentiation

2 references

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0K7&geneProductId=UniProtKB:Q9R0K7

cellular calcium ion homeostasis

3 references

14 February 2019

A mouse with a point mutation in plasma membrane Ca2+-ATPase isoform 2 gene showed the reduced Ca2+ influx in cerebellar neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

regulation of cytosolic calcium ion concentration

IBA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

regulation of presynaptic cytosolic calcium ion concentration

IBA

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7

regulation of postsynaptic cytosolic calcium ion concentration

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0K7