Aldehyde dehydrogenase family 1, subfamily A3 (Q21498952)

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mammalian protein found in Mus musculus

Aldh1a3
aldehyde dehydrogenase-6
aldehyde dehydrogenase family 1 member A3
retinaldehyde dehydrogenase 3
RalDH3
RALDH-3
Aldehyde dehydrogenase 6

Language	Label	Description	Also known as
English	Aldehyde dehydrogenase family 1, subfamily A3	mammalian protein found in Mus musculus	Aldh1a3 aldehyde dehydrogenase-6 aldehyde dehydrogenase family 1 member A3 retinaldehyde dehydrogenase 3 RalDH3 RALDH-3 Aldehyde dehydrogenase 6

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Aldehyde/histidinol dehydrogenase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Aldehyde dehydrogenase NAD(P)-dependent

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Aldehyde dehydrogenase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Aldehyde dehydrogenase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Aldehyde dehydrogenase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aldehyde dehydrogenase, glutamic acid active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Aldehyde dehydrogenase, cysteine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

3-chloroallyl aldehyde dehydrogenase activity

determination method

1 reference

9 May 2019

A retinoic acid synthesizing enzyme in ventral retina and telencephalon of the embryonic mouse

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

aldehyde dehydrogenase [NAD(P)+] activity

determination method

3 references

determination method

1 reference

9 May 2019

Characterization of retinaldehyde dehydrogenase 3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

thyroid hormone binding

determination method

1 reference

9 May 2019

Characterization of retinaldehyde dehydrogenase 3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

retinal dehydrogenase activity

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

aldehyde dehydrogenase (NAD+) activity

determination method

3 references

9 May 2019

Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Characterization of retinaldehyde dehydrogenase 3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

determination method

4 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

biological process

locomotory behavior

determination method

1 reference

9 May 2019

Retinoic acid deficiency impairs the vestibular function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

neuromuscular process controlling balance

determination method

1 reference

9 May 2019

Retinoic acid deficiency impairs the vestibular function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

retinol metabolic process

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

embryonic eye morphogenesis

determination method

4 references

9 May 2019

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

nucleus accumbens development

determination method

1 reference

9 May 2019

Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

retinoic acid metabolic process

determination method

5 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

olfactory pit development

determination method

1 reference

9 May 2019

Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

cellular aldehyde metabolic process

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

face development

determination method

1 reference

9 May 2019

Retinoids control anterior and dorsal properties in the developing forebrain

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

inner ear morphogenesis

determination method

1 reference

9 May 2019

Retinoic acid deficiency impairs the vestibular function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

positive regulation of apoptotic process

determination method

3 references

9 May 2019

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

optic cup morphogenesis involved in camera-type eye development

determination method

1 reference

9 May 2019

Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

determination method

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9JHW9&geneProductId=UniProtKB:Q9JHW9

determination method

righting reflex

determination method

1 reference

9 May 2019

Retinoic acid deficiency impairs the vestibular function

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

embryonic camera-type eye development

determination method

nose development

determination method

1 reference

9 May 2019

A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

Harderian gland development

determination method

1 reference

9 May 2019

A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

retinoic acid biosynthetic process

determination method

6 references

9 May 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Identification of RALDH-3, a novel retinaldehyde dehydrogenase, expressed in the ventral region of the retina

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

9 May 2019

Characterization of retinaldehyde dehydrogenase 3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

protein homotetramerization

determination method

positive regulation of retinoic acid receptor signaling pathway

determination method

1 reference

9 May 2019

Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9JHW9

determination method

Aldehyde dehydrogenase, glutamic acid active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Aldehyde dehydrogenase, cysteine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Aldehyde dehydrogenase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9JHW9

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000015278

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000015278

ENSMUSP00000133370

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133370

ENSMUSP00000146703

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000146703

ENSMUSP00000146806

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000146806

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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