Zinc finger protein, multitype 2 (Q21498475)

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mammalian protein found in Mus musculus

zinc finger protein ZFPM2
Zinc finger protein multitype 2
FOG-2
friend of GATA protein 2
Zfpm2
friend of GATA-1 2
Friend of GATA 2
mFOG-2
friend of GATA-2

Language	Label	Description	Also known as
English	Zinc finger protein, multitype 2	mammalian protein found in Mus musculus	zinc finger protein ZFPM2 Zinc finger protein multitype 2 FOG-2 friend of GATA protein 2 Zfpm2 friend of GATA-1 2 Friend of GATA 2 mFOG-2 friend of GATA-2

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

transcription factor binding

determination method

3 references

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

protein binding

determination method

nucleic acid binding

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

transcription corepressor activity

determination method

3 references

24 April 2018

Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

transcription corepressor activity

determination method

3 references

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

determination method

1 reference

14 February 2019

Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

determination method

2 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

determination method

7 references

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

determination method

6 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

biological process

negative regulation of fat cell differentiation

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

regulation of transcription, DNA-templated

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

lung development

determination method

1 reference

14 February 2019

Fog2 is required for normal diaphragm and lung development in mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

cardiac muscle tissue development

determination method

1 reference

14 February 2019

Fog2 is required for normal diaphragm and lung development in mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

outflow tract morphogenesis

determination method

1 reference

14 February 2019

Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

cardiac muscle tissue morphogenesis

determination method

1 reference

14 February 2019

Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

in utero embryonic development

determination method

1 reference

14 February 2019

Fog2 is required for normal diaphragm and lung development in mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

negative regulation of transcription by RNA polymerase II

determination method

3 references

24 April 2018

Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

negative regulation of cell death

determination method

1 reference

14 February 2019

GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

transcription, DNA-templated

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

heart development

determination method

3 references

24 April 2018

Fog2 is required for normal diaphragm and lung development in mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

24 April 2018

FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CCH7&geneProductId=UniProtKB:Q8CCH7

determination method

negative regulation of female gonad development

determination method

1 reference

14 February 2019

Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

atrioventricular valve morphogenesis

determination method

1 reference

14 February 2019

Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

mitral valve formation

determination method

1 reference

14 February 2019

Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

tricuspid valve formation

determination method

1 reference

14 February 2019

Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

negative regulation of transcription, DNA-templated

determination method

3 references

vasculogenesis involved in coronary vascular morphogenesis

determination method

1 reference

14 February 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

positive regulation of male gonad development

determination method

1 reference

14 February 2019

Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

positive regulation of transcription by RNA polymerase II

determination method

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

positive regulation of cardiac muscle cell proliferation

determination method

1 reference

14 February 2019

The miR-17-92 cluster regulates FOG-2 expression and inhibits proliferation of mouse embryonic cardiomyocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

negative regulation of transcription by RNA polymerase II

determination method

4 references

14 February 2019

FOG-2 and GATA-4 Are coexpressed in the mouse ovary and can modulate mullerian-inhibiting substance expression

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

heart development

determination method

4 references

14 February 2019

A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Fog2 is required for normal diaphragm and lung development in mice and humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CCH7

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000051335

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000051335

ENSMUSP00000155094

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000155094

Sitelinks

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