Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin (Q21284382)

18 August 2022

Robin Kuns-Hashimoto

series ordinal

2

author given names

Robin

author last names

Kuns-Hashimoto

1 reference

18 August 2022

Mahta Nili

series ordinal

3

author given names

Mahta

author last names

Nili

1 reference

18 August 2022

Peter Rotwein

series ordinal

4

author given names

Peter

author last names

Rotwein

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2091-9-9

18 August 2022

language of work or name

English

0 references

publication date

2008

0 references

published in

BMC Biochemistry

0 references

volume

9

0 references

page(s)

9

0 references

issue

1

0 references

exact match

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1471-2091-9-9

cites work

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1 reference

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Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site

19 March 2017

1 reference

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Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

19 March 2017

1 reference

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Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

19 March 2017

1 reference

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A mouse model of juvenile hemochromatosis

19 March 2017

1 reference

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Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

19 March 2017

1 reference

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Furin at the cutting edge: from protein traffic to embryogenesis and disease

19 March 2017

1 reference

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Hepcidin, a urinary antimicrobial peptide synthesized in the liver

19 March 2017

1 reference

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Complex biosynthesis of the muscle-enriched iron regulator RGMc

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system

19 March 2017

1 reference

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Isolation and expression pattern of three mouse homologues of chick Rgm

19 March 2017

1 reference

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Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

19 March 2017

1 reference

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Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides

19 March 2017

1 reference

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Balancing acts: molecular control of mammalian iron metabolism

19 March 2017

1 reference

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Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Hemochromatosis: genetics and pathophysiology

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

Shedding of the transferrin receptor is mediated constitutively by an integral membrane metalloprotease sensitive to tumor necrosis factor alpha protease inhibitor-2.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323002

HJV gene mutations in European patients with juvenile hemochromatosis

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18384687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Three patients with middle-age-onset hemochromatosis caused by novel mutations in the hemojuvelin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18384687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18384687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2091-9-9

0 references