Ficolin 2 (Q21201082)

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mammalian protein found in Homo sapiens

ficolin B
L-ficolin
37 kDa elastin-binding protein
Hucolin
ficolin-2
ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
FCN2
collagen/fibrinogen domain-containing protein 2
Ficolin-B
ficolin-beta
serum lectin p35
EBP-37

Language	Label	Description	Also known as
English	Ficolin 2	mammalian protein found in Homo sapiens	ficolin B L-ficolin 37 kDa elastin-binding protein Hucolin ficolin-2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) FCN2 collagen/fibrinogen domain-containing protein 2 Ficolin-B ficolin-beta serum lectin p35 EBP-37

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

Fibrinogen-like, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15485

Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15485

Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fibrinogen, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

collagen triple helix repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

antigen binding

determination method

1 reference

8 April 2019

A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

protein binding

determination method

3 references

8 April 2019

Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

8 April 2019

M-ficolin interacts with the long pentraxin PTX3: a novel case of cross-talk between soluble pattern-recognition molecules

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

8 April 2019

CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

determination method

1 reference

8 April 2019

A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

calcium-dependent protein binding

determination method

1 reference

8 April 2019

Characterization of the interaction between L-ficolin/p35 and mannan-binding lectin-associated serine proteases-1 and -2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

carbohydrate binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

proteoglycan binding

determination method

1 reference

8 April 2019

A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

serine-type endopeptidase activity

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15485&geneProductId=UniProtKB:Q15485

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

blood microparticle

determination method

1 reference

26 September 2017

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15485&geneProductId=UniProtKB:Q15485

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

blood microparticle

determination method

1 reference

8 April 2019

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

biological process

immune system process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

complement activation, lectin pathway

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

8 April 2019

Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

8 April 2019

L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

complement activation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

recognition of apoptotic cell

determination method

1 reference

8 April 2019

Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

determination method

1 reference

8 April 2019

A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

defense response to Gram-positive bacterium

determination method

1 reference

8 April 2019

L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

innate immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15485

determination method

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15485&geneProductId=UniProtKB:Q15485

determination method

Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15485

Fibrinogen, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15485

Collagen triple helix repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15485

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000291741

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000291741

ENSP00000291744

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000291744

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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