Alkaline ceramidase 1 (Q21172630)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

N-acylsphingosine amidohydrolase (alkaline ceramidase) 3
alkaline CDase 1
alkaline ceramidase 1
CTB-180A7.3
ACER1
alkCDase 1
N-acylsphingosine amidohydrolase 3
acylsphingosine deacylase 3

Language	Label	Description	Also known as
English	Alkaline ceramidase 1	mammalian protein found in Homo sapiens	N-acylsphingosine amidohydrolase (alkaline ceramidase) 3 alkaline CDase 1 alkaline ceramidase 1 CTB-180A7.3 ACER1 alkCDase 1 N-acylsphingosine amidohydrolase 3 acylsphingosine deacylase 3

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TDN7

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

dihydroceramidase activity

determination method

1 reference

7 November 2018

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDN7&geneProductId=UniProtKB:Q8TDN7

determination method

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

N-acylsphingosine amidohydrolase activity

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

ceramidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

dihydroceramidase activity

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

endoplasmic reticulum

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

biological process

cellular response to calcium ion

determination method

1 reference

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

regulation of lipid metabolic process

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

cell differentiation

determination method

1 reference

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

sphingosine biosynthetic process

determination method

2 references

7 November 2018

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDN7&geneProductId=UniProtKB:Q8TDN7

determination method

7 November 2018

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TDN7&geneProductId=UniProtKB:Q8TDN7

determination method

response to alkaline pH

determination method

1 reference

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

keratinocyte differentiation

determination method

1 reference

8 April 2019

Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

ceramide metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

epidermis development

determination method

1 reference

8 April 2019

Differentiation-associated expression of ceramidase isoforms in cultured keratinocytes and epidermis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

lipid metabolism

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

sphingolipid metabolic process

determination method

regulation of water loss via skin

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

sphingosine biosynthetic process

determination method

4 references

8 April 2019

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

ceramide catabolic process

determination method

3 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

sebaceous gland development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TDN7

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000301452

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000301452

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21172630&oldid=2023035158"