Exosome component 2 (Q21172308)

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mammalian protein found in Homo sapiens
  • ribosomal RNA-processing protein 4
  • homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease
  • exosome complex component RRP4
  • EXOSC2
  • exosome complex exonuclease RRP4
  • homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4)
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Language Label Description Also known as
English
Exosome component 2
mammalian protein found in Homo sapiens
  • ribosomal RNA-processing protein 4
  • homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease
  • exosome complex component RRP4
  • EXOSC2
  • exosome complex exonuclease RRP4
  • homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4)

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
8 April 2019
stated in
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1
GOA
curator
UniProt
UniProt protein ID
Q13868
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2
GOA
curator
UniProt
UniProt protein ID
Q13868
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
Dis3-like 1: a novel exoribonuclease associated with the human exosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
A protein interaction framework for human mRNA degradation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
retrieved
8 April 2019
stated in
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13868
determination method
IPI
cell component
biological process

Identifiers

 
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