YME1 like 1 ATPase (Q21136882)

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mammalian protein found in Homo sapiens

PAMP
ATP-dependent metalloprotease FtsH1 homolog
meg-4
YME1-like protein 1
presenilin-associated metalloprotease
ATP-dependent metalloprotease FtsH1
YME1L1
ATP-dependent zinc metalloprotease YME1L1

Language	Label	Description	Also known as
English	YME1 like 1 ATPase	mammalian protein found in Homo sapiens	PAMP ATP-dependent metalloprotease FtsH1 homolog meg-4 YME1-like protein 1 presenilin-associated metalloprotease ATP-dependent metalloprotease FtsH1 YME1L1 ATP-dependent zinc metalloprotease YME1L1

Statements

1 reference

13 November 2019

UniProt protein ID

Peptidase, FtsH

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96TA2

Peptidase M41-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96TA2

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96TA2

ATPase, AAA-type, core domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase M41 family

1 reference

based on heuristic

inferred from protein domain or family

ATPase, AAA-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

metallopeptidase activity

determination method

2 references

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

metalloendopeptidase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

determination method

2 references

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

protein binding

determination method

1 reference

8 April 2019

The mammalian homologue of yeast Afg1 ATPase (lactation elevated 1) mediates degradation of nuclear-encoded complex IV subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

ATP-dependent peptidase activity

determination method

4 references

8 April 2019

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

metallopeptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

determination method

4 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

determination method

3 references

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

mitochondrial inner membrane

determination method

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

26 September 2017

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

mitochondrial inner membrane

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

determination method

biological process

mitochondrion organization

determination method

2 references

determination method

2 references

cell population proliferation

determination method

1 reference

8 April 2019

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

protein quality control for misfolded or incompletely synthesized proteins

determination method

1 reference

26 September 2017

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96TA2&geneProductId=UniProtKB:Q96TA2

determination method

mitochondrial protein catabolic process

determination method

mitochondrial calcium ion transmembrane transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

negative regulation of apoptotic process

determination method

1 reference

8 April 2019

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

protein hexamerization

determination method

1 reference

8 April 2019

Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

determination method

protein quality control for misfolded or incompletely synthesized proteins

determination method

mitochondrion organization

determination method

3 references

8 April 2019

YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96TA2

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000318480

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000318480

ENSP00000365184

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000365184

ENSP00000481724

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000481724

ENSP00000365139

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000365139

ENSP00000379590

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000379590

ENSP00000398713

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398713

ENSP00000473302

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473302

ENSP00000473557

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473557

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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