Human RSPO1/R-spondin1 is expressed during early ovary development and augments β-catenin signaling (Q21135743)

ORCID Public Data File 2021

17 August 2022

5

Dianne

Gerrelli

Dianne Gerrelli

1 reference

17 August 2022

Sara Tomaselli

1

Sara

Tomaselli

1 reference

17 August 2022

Lin Lin

series ordinal

3

author given names

Lin

author last names

Lin

1 reference

17 August 2022

Maria Cristina Mazzilli

series ordinal

4

author given names

Maria Cristina

author last names

Mazzilli

1 reference

17 August 2022

Paola Grammatico

series ordinal

7

author given names

Paola

author last names

Grammatico

1 reference

17 August 2022

language of work or name

English

0 references

publication date

2011

0 references

published in

PLOS One

0 references

volume

6

0 references

page(s)

e16366

0 references

issue

1

0 references

copyright license

Creative Commons Attribution 4.0 International

start time

28 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression

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WNT4 is expressed in human fetal and adult ovaries and its signaling contributes to ovarian cell survival

19 March 2017

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Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1) gene transcription is regulated by wnt4 in the female developing gonad

19 March 2017

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Female development in mammals is regulated by Wnt-4 signalling

19 March 2017

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Dax1 antagonizes Sry action in mammalian sex determination

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A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal

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R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants

19 March 2017

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Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice

19 March 2017

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R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/beta-catenin pathway

12 September 2017

1 reference

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Genetics of ovarian differentiation: Rspo1, a major player

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Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian development

12 September 2017

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Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal

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12 September 2017

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R-Spondin family members regulate the Wnt pathway by a common mechanism

12 September 2017

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R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation

12 September 2017

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The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia

12 September 2017

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R-spondin1 is essential in sex determination, skin differentiation and malignancy.

12 September 2017

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12 September 2017

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R-Spondin proteins: a novel link to beta-catenin activation

12 September 2017

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Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development

12 September 2017

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R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

12 September 2017

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12 September 2017

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12 September 2017

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R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression

12 September 2017

1 reference

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Panning transfected cells for electrophysiological studies

27 September 2017

1 reference

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R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016366

Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016366

R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016366

Syndromic true hermaphroditism due to an R-spondin1 (RSPO1) homozygous mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016366

R-spondin1, a novel intestinotrophic mitogen, ameliorates experimental colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016366

Goat RSPO1 over-expression rescues sex-reversal in Rspo1-knockout XX mice but does not perturb testis differentiation in XY or sex-reversed XX mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016366

R-spondin1 is required for normal epithelial morphogenesis during mammary gland development

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21297984

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

46,XY disorders of sex development (DSD)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21297984

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0016366

1 reference

release_2hokfmiwl5bwdnzpyu2vxhm7oq

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2hokfmiwl5bwdnzpyu2vxhm7oq

mapped directly with Wikidata item

24 November 2022

based on heuristic

4793825

1 reference

1 reference

1 reference