Spermatogenesis associated 13 (Q21135680)

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mammalian protein found in Homo sapiens

SPATA13
spermatogenesis-associated protein 13
Asef2
adenomatous polyposis coli stimulated exchange factor 2
APC-stimulated guanine nucleotide exchange factor 2

Language	Label	Description	Also known as
English	Spermatogenesis associated 13	mammalian protein found in Homo sapiens	SPATA13 spermatogenesis-associated protein 13 Asef2 adenomatous polyposis coli stimulated exchange factor 2 APC-stimulated guanine nucleotide exchange factor 2

Statements

1 reference

13 November 2019

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96N96

Dbl homology (DH) domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96N96

PH-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96N96

membrane proteins

1 reference

based on heuristic

inferred from GOA cell component → membrane

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dbl homology (DH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

5 references

8 April 2019

Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

guanyl-nucleotide exchange factor activity

determination method

4 references

8 April 2019

Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

The Rho-family GEF Asef2 activates Rac to modulate adhesion and actin dynamics and thereby regulate cell migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

identical protein binding

determination method

1 reference

27 March 2018

Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96N96&geneProductId=UniProtKB:Q96N96

determination method

plasma membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

cell projection

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

8 April 2019

Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

biological process

filopodium assembly

determination method

regulation of Rho protein signal transduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

regulation of cell migration

determination method

determination method

lamellipodium assembly

determination method

1 reference

8 April 2019

Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96N96

determination method

pleckstrin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96N96

Dbl homology (DH) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96N96

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q96N96

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000401605

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401605

ENSP00000398560

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398560

ENSP00000477296

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477296

ENSP00000397498

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397498

ENSP00000343631

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000343631

ENSP00000382830

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000382830

ENSP00000477304

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477304

ENSP00000386471

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386471

ENSP00000371527

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000371527

ENSP00000371542

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000371542

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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