Synaptosome associated protein 23 (Q21135056)

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mammalian protein found in Homo sapiens

synaptosomal-associated protein, 23kDa
synaptosomal-associated protein 23
vesicle-membrane fusion protein SNAP-23
synaptosomal-associated protein, 23kD
synaptosome associated protein 23kDa
SNAP23

Language	Label	Description	Also known as
English	Synaptosome associated protein 23	mammalian protein found in Homo sapiens	synaptosomal-associated protein, 23kDa synaptosomal-associated protein 23 vesicle-membrane fusion protein SNAP-23 synaptosomal-associated protein, 23kD synaptosome associated protein 23kDa SNAP23

Statements

1 reference

13 November 2019

UniProt protein ID

synaptosomal vesicle fusion pore

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

SNAP-25 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Target SNARE coiled-coil homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

SNAP receptor activity

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

protein binding

determination method

7 references

1 January 2018

A role for Sec1/Munc18 proteins in platelet exocytosis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

SNAP-23 and VAMP-3 contribute to the release of IL-6 and TNFα from a human synovial sarcoma cell line

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

A directed protein interaction network for investigating intracellular signal transduction

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

The Q-soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor (Q-SNARE) SNAP-47 Regulates Trafficking of Selected Vesicle-associated Membrane Proteins (VAMPs).

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

syntaxin binding

determination method

1 reference

26 September 2017

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

Heterogeneous expression of SNARE proteins SNAP-23, SNAP-25, Syntaxin1 and VAMP in human parathyroid tissue

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

26 September 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

plasma membrane

determination method

6 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

Heterogeneous expression of SNARE proteins SNAP-23, SNAP-25, Syntaxin1 and VAMP in human parathyroid tissue

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

26 September 2017

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

azurophil granule

determination method

1 reference

1 January 2018

Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

specific granule

determination method

1 reference

1 January 2018

Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

neuron projection

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

extracellular exosome

determination method

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

26 September 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

mast cell granule

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

phagocytic vesicle membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

specific granule membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

tertiary granule membrane

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

plasma membrane

determination method

7 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

Heterogeneous expression of SNARE proteins SNAP-23, SNAP-25, Syntaxin1 and VAMP in human parathyroid tissue

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

biological process

histamine secretion by mast cell

determination method

1 reference

1 January 2018

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

vesicle targeting

determination method

1 reference

1 January 2018

Identification of a novel syntaxin- and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

synaptic vesicle fusion to presynaptic active zone membrane

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

membrane fusion

determination method

1 reference

1 January 2018

SNAREs contribute to the specificity of membrane fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

synaptic vesicle priming

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

protein transport

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

neutrophil degranulation

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00161&geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00161

determination method

Target SNARE coiled-coil homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00161

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00161

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000207062

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000207062

ENSP00000249647

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000249647

ENSP00000380327

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000380327

ENSP00000454214

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454214

ENSP00000454799

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454799

ENSP00000454842

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454842

ENSP00000455102

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455102

ENSP00000455339

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455339

ENSP00000455472

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455472

ENSP00000455652

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455652

ENSP00000456000

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456000

ENSP00000456035

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456035

ENSP00000456144

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456144

ENSP00000457535

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000457535

ENSP00000458012

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000458012

ENSP00000485888

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000485888

ENSP00000486335

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486335

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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