Nuclear factor, erythroid 4 (Q21133486)

mammalian protein found in Homo sapiens

gamma-globin gene activator
fetal globin activator NF-E4
transcription factor NF-E4
NFE4

Language	Label	Description	Also known as
English	Nuclear factor, erythroid 4	mammalian protein found in Homo sapiens	gamma-globin gene activator fetal globin activator NF-E4 transcription factor NF-E4 NFE4

Statements

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

13 November 2019

cis-regulatory region sequence-specific DNA binding

2 references

27 February 2018

Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86UQ8&geneProductId=UniProtKB:Q86UQ8

27 February 2018

Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86UQ8&geneProductId=UniProtKB:Q86UQ8

determination method

IDA

DNA-binding transcription factor activity

3 references

8 April 2019

Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

8 April 2019

Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

8 April 2019

Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

protein homodimerization activity

1 reference

8 April 2019

Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

determination method

IDA

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Site-specific acetylation of the fetal globin activator NF-E4 prevents its ubiquitination and regulates its interaction with the histone deacetylase, HDAC1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

determination method

IMP

cell component

protein-containing complex

transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86UQ8&geneProductId=UniProtKB:Q86UQ8

determination method

IEA

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Repression of human gamma-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

determination method

IMP

positive regulation of transcription by RNA polymerase II

determination method

IDA

IMP

protein-containing complex assembly

1 reference

8 April 2019

Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

determination method

IDA

regulation of transcription, DNA-templated

1 reference

8 April 2019

The role of p22 NF-E4 in human globin gene switching

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86UQ8

determination method

IDA

Identifiers

1 reference

22 November 2019

1 reference

13 November 2019

1 reference

Nuclear factor, erythroid 4 (Q21133486)

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Nuclear factor, erythroid 4 (Q21133486)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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