Steroid receptor RNA activator 1 (Q21132834)

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mammalian protein found in Homo sapiens

steroid receptor coactivator
steroid receptor RNA activator protein
steroid receptor RNA activator 1
steroid receptor RNA activator 1 (complexes with NCOA1)
SRAP
SRA1

Language	Label	Description	Also known as
English	Steroid receptor RNA activator 1	mammalian protein found in Homo sapiens	steroid receptor coactivator steroid receptor RNA activator protein steroid receptor RNA activator 1 steroid receptor RNA activator 1 (complexes with NCOA1) SRAP SRA1

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transcription coactivator activity

determination method

1 reference

8 April 2019

A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

protein binding

determination method

2 references

8 April 2019

Orphan nuclear receptor Nur77 induces zinc finger protein GIOT-1 gene expression, and GIOT-1 acts as a novel corepressor of orphan nuclear receptor SF-1 via recruitment of HDAC2

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

The steroid receptor RNA activator protein is recruited to promoter regions and acts as a transcriptional repressor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

nuclear receptor coactivator activity

determination method

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

steroid receptor RNA activator RNA binding

determination method

3 references

8 April 2019

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

The C-terminal domain of SRA1p has a fold more similar to PRP18 than to an RRM and does not directly bind to the SRA1 RNA STR7 region

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

nuclear receptor coactivator activity

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

microtubule cytoskeleton

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

intercellular bridge

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

plasma membrane

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

determination method

3 references

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

5 June 2018

Identification of new human coding steroid receptor RNA activator isoforms

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

5 June 2018

Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

ribonucleoprotein complex

determination method

3 references

8 April 2019

A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

Identification of new human coding steroid receptor RNA activator isoforms

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

transcription regulator complex

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

cell leading edge

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

biological process

regulation of apoptotic process

determination method

1 reference

8 April 2019

Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

cell differentiation

determination method

1 reference

8 April 2019

Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

positive regulation of signaling receptor activity

determination method

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

cell population proliferation

determination method

1 reference

8 April 2019

Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

regulation of transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

transcription, DNA-templated

determination method

1 reference

5 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9HD15&geneProductId=UniProtKB:Q9HD15

determination method

apoptotic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

negative regulation of myoblast differentiation

determination method

1 reference

8 April 2019

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

cellular response to estrogen stimulus

determination method

1 reference

8 April 2019

Structure and Function of Steroid Receptor RNA Activator Protein, the Proposed Partner of SRA Noncoding RNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

positive regulation of nucleic acid-templated transcription

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9HD15

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000337513

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000337513

ENSP00000473378

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000473378

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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