Ferritin heavy chain 1 (Q21131906)

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mammalian protein found in Homo sapiens

placenta immunoregulatory factor
ferritin heavy chain
apoferritin
cell proliferation-inducing gene 15 protein
ferritin, heavy polypeptide 1
ferritin H subunit
proliferation-inducing protein 15
FTH1

Language	Label	Description	Also known as
English	Ferritin heavy chain 1	mammalian protein found in Homo sapiens	placenta immunoregulatory factor ferritin heavy chain apoferritin cell proliferation-inducing gene 15 protein ferritin, heavy polypeptide 1 ferritin H subunit proliferation-inducing protein 15 FTH1

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02794

Ferritin-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02794

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02794

Ferritin-like diiron domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ferritin/DPS protein domain family

1 reference

based on heuristic

inferred from protein domain or family

Ferritin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

ferric iron binding

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

ferroxidase activity

determination method

1 reference

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

protein binding

determination method

12 references

8 April 2019

A human protein-protein interaction network: a resource for annotating the proteome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Binding and uptake of H-ferritin are mediated by human transferrin receptor-1.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

FTH1 binds to Daxx and inhibits Daxx-mediated cell apoptosis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

A comprehensive resource of interacting protein regions for refining human transcription factor networks

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

oxidoreductase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

iron ion binding

determination method

1 reference

17 October 2017

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

ferrous iron binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

identical protein binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

intracellular ferritin complex

determination method

1 reference

8 April 2019

Isolation and characterization of a cDNA clone for human ferritin heavy chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

extracellular exosome

determination method

3 references

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

determination method

1 reference

17 October 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

extracellular region

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

determination method

1 reference

8 April 2019

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

tertiary granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

ficolin-1-rich granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

determination method

1 reference

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

biological process

intracellular sequestering of iron ion

determination method

1 reference

17 October 2017

Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P02794&geneProductId=UniProtKB:P02794

determination method

iron ion transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

immune response

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

negative regulation of fibroblast proliferation

determination method

1 reference

8 April 2019

Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

negative regulation of cell population proliferation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

cellular iron ion homeostasis

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

Isolation and characterization of a cDNA clone for human ferritin heavy chain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

neutrophil degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

negative regulation of necrotic cell death

determination method

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02794

determination method

ferritin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02794

ferritin/DPS protein domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02794

ferritin-like diiron domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P02794

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000273550

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000273550

ENSP00000484477

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484477

ENSP00000431575

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431575

ENSP00000431659

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431659

ENSP00000432223

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000432223

ENSP00000433321

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433321

ENSP00000433470

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433470

ENSP00000434403

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434403

ENSP00000435111

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435111

ENSP00000436947

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000436947

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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