Ring finger protein 213 (Q21127044)

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mammalian protein found in Homo sapiens

E3 ubiquitin-protein ligase RNF213
RNF213
ALK lymphoma oligomerization partner on chromosome 17
mysterin
RING finger protein 213
RING-type E3 ubiquitin transferase RNF213

Language	Label	Description	Also known as
English	Ring finger protein 213	mammalian protein found in Homo sapiens	E3 ubiquitin-protein ligase RNF213 RNF213 ALK lymphoma oligomerization partner on chromosome 17 mysterin RING finger protein 213 RING-type E3 ubiquitin transferase RNF213

Statements

1 reference

13 November 2019

UniProt protein ID

Zinc finger, RING/FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q63HN8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q63HN8

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q63HN8

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, C3HC4 RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

1 reference

26 September 2017

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

ATPase activity

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

ubiquitin-protein transferase activity

determination method

5 references

26 September 2017

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

26 September 2017

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

26 September 2017

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

ubiquitin-protein transferase activity

determination method

6 references

1 January 2018

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

1 January 2018

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

1 January 2018

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

ubiquitin-protein transferase activity

determination method

4 references

8 April 2019

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

determination method

1 reference

26 September 2017

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

determination method

1 reference

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

determination method

3 references

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

determination method

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

biological process

ubiquitin-dependent protein catabolic process

determination method

1 reference

26 September 2017

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

negative regulation of non-canonical Wnt signaling pathway

determination method

1 reference

26 September 2017

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

determination method

3 references

8 April 2019

Moyamoya disease susceptibility gene RNF213 links inflammatory and angiogenic signals in endothelial cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

sprouting angiogenesis

determination method

1 reference

26 September 2017

Endothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT Signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q63HN8&geneProductId=UniProtKB:Q63HN8

determination method

protein homooligomerization

determination method

protein autoubiquitination

determination method

1 reference

8 April 2019

Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

protein polyubiquitination

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63HN8

determination method

negative regulation of non-canonical Wnt signaling pathway

determination method

Zinc finger, C3HC4 RING-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q63HN8

AAA+ ATPase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q63HN8

Zinc finger, RING-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q63HN8

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000324392

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000324392

ENSP00000425956

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425956

ENSP00000460462

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460462

ENSP00000464087

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464087

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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