Serine protease 3 (Q21125508)

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mammalian protein found in Homo sapiens

mesotrypsin
trypsin III
mesotrypsinogen
trypsin-3
Serine protease 4
trypsinogen 4
trypsinogen 5
pancreatic trypsinogen III
trypsin IV
protease, serine, 4 (trypsin 4, brain)
protease, serine 3
brain trypsinogen
trypsinogen IV
PRSS3

Language	Label	Description	Also known as
English	Serine protease 3	mammalian protein found in Homo sapiens	mesotrypsin trypsin III mesotrypsinogen trypsin-3 Serine protease 4 trypsinogen 4 trypsinogen 5 pancreatic trypsinogen III trypsin IV protease, serine, 4 (trypsin 4, brain) protease, serine 3 brain trypsinogen trypsinogen IV PRSS3

Statements

1 reference

13 November 2019

UniProt protein ID

peptidase S1A, chymotrypsin family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35030

Peptidase S1, PA clan

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35030

Serine proteases, trypsin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine proteases, trypsin family, histidine active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

serine-type endopeptidase activity

determination method

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

serine-type peptidase activity

determination method

3 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

Identification and expression of the cDNA-encoding human mesotrypsin(ogen), an isoform of trypsin with inhibitor resistance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

serine-type endopeptidase activity

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Crystal structure reveals basis for the inhibitor resistance of human brain trypsin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

serine-type peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

extracellular space

determination method

1 reference

27 March 2018

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

tertiary granule lumen

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

biological process

determination method

4 references

8 April 2019

Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Nucleotide sequence of the human pancreatic trypsinogen III cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

cobalamin metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

zymogen activation

determination method

1 reference

8 April 2019

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

endothelial cell migration

determination method

1 reference

8 April 2019

S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

determination method

6 references

27 March 2018

Nucleotide sequence of the human pancreatic trypsinogen III cDNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

Cloning of the cDNA encoding human brain trypsinogen and characterization of its product

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

27 March 2018

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35030&geneProductId=UniProtKB:P35030

determination method

antimicrobial humoral response

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

neutrophil degranulation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

determination method

7 references

8 April 2019

Nucleotide sequence of the human pancreatic trypsinogen III cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Cloning of the cDNA encoding human brain trypsinogen and characterization of its product

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Crystal structure reveals basis for the inhibitor resistance of human brain trypsin

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Mesotrypsin: a new inhibitor-resistant protease from a zymogen in human pancreatic tissue and fluid

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35030

determination method

serine proteases, trypsin family, histidine active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35030

serine proteases, trypsin domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35030

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000340889

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000340889

ENSP00000354280

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000354280

ENSP00000368715

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000368715

ENSP00000401828

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401828

ENSP00000401249

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401249

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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