RAB3 GTPase activating protein catalytic subunit 1 (Q21125019)

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mammalian protein found in Homo sapiens

RAB3 GTPase-activating protein 130 kDa subunit
RAB3 GTPase activating protein subunit 1 (catalytic)
RAB3GAP1
Rab3-GAP
rab3-GAP p130
rab3 GTPase-activating protein catalytic subunit

Language	Label	Description	Also known as
English	RAB3 GTPase activating protein catalytic subunit 1	mammalian protein found in Homo sapiens	RAB3 GTPase-activating protein 130 kDa subunit RAB3 GTPase activating protein subunit 1 (catalytic) RAB3GAP1 Rab3-GAP rab3-GAP p130 rab3 GTPase-activating protein catalytic subunit

Statements

1 reference

13 November 2019

UniProt protein ID

Rab3 GTPase-activating protein catalytic subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q15042

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

guanyl-nucleotide exchange factor activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

GTPase activator activity

determination method

6 references

31 October 2017

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

protein binding

determination method

1 reference

8 April 2019

Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

GTPase activator activity

determination method

7 references

8 April 2019

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

Golgi apparatus

determination method

1 reference

8 April 2019

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

determination method

1 reference

8 April 2019

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

endoplasmic reticulum tubular network

determination method

1 reference

8 April 2019

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

extracellular exosome

determination method

1 reference

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

endoplasmic reticulum membrane

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

protein-containing complex

determination method

1 reference

8 April 2019

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

biological process

positive regulation of autophagosome assembly

determination method

1 reference

8 April 2019

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

lipid droplet organization

determination method

1 reference

8 April 2019

Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

regulation of GTPase activity

determination method

1 reference

8 April 2019

Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

positive regulation of protein lipidation

determination method

1 reference

8 April 2019

RAB3GAP1 and RAB3GAP2 modulate basal and rapamycin-induced autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

brain development

determination method

1 reference

8 April 2019

New RAB3GAP1 mutations in patients with Warburg Micro Syndrome from different ethnic backgrounds and a possible founder effect in the Danish

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

positive regulation of gene expression

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

positive regulation of endoplasmic reticulum tubular network organization

determination method

1 reference

8 April 2019

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

hypothalamus development

determination method

1 reference

8 April 2019

New RAB3GAP1 mutations in patients with Warburg Micro Syndrome from different ethnic backgrounds and a possible founder effect in the Danish

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

establishment of protein localization to endoplasmic reticulum membrane

determination method

1 reference

8 April 2019

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

camera-type eye development

determination method

1 reference

8 April 2019

New RAB3GAP1 mutations in patients with Warburg Micro Syndrome from different ethnic backgrounds and a possible founder effect in the Danish

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

face morphogenesis

determination method

1 reference

8 April 2019

New RAB3GAP1 mutations in patients with Warburg Micro Syndrome from different ethnic backgrounds and a possible founder effect in the Danish

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

positive regulation of GTPase activity

determination method

3 references

31 October 2017

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

31 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15042&geneProductId=UniProtKB:Q15042

determination method

positive regulation of GTPase activity

determination method

4 references

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Rab18 and a Rab18 GEF complex are required for normal ER structure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15042

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000264158

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000264158

ENSP00000411418

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411418

ENSP00000444306

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000444306

ENSP00000400761

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400761

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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