Sorting nexin 6 (Q21123671)

protein homodimerization activity

IDA

1 reference

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 references

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Sorting nexin 6 interacts with breast cancer metastasis suppressor-1 and promotes transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

PtdIns(4)P regulates retromer-motor interaction to facilitate dynein-cargo dissociation at the trans-Golgi network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

protein heterodimerization activity

IPI

1 reference

9 May 2019

Retromer: Structure, function, and roles in mammalian disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

phosphatidylinositol binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Sorting nexin 6 interacts with breast cancer metastasis suppressor-1 and promotes transcriptional repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

retromer, tubulation complex

1 reference

9 May 2019

Retromer: Structure, function, and roles in mammalian disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

intracellular anatomical structure

1 reference

1 January 2018

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UNH7&geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

extrinsic component of membrane

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UNH7&geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UNH7&geneProductId=UniProtKB:Q9UNH7

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UNH7&geneProductId=UniProtKB:Q9UNH7

negative regulation of transforming growth factor beta receptor signaling pathway

IBA

1 reference

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

negative regulation of epidermal growth factor-activated receptor activity

IDA

1 reference

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

intracellular protein transport

3 references

9 May 2019

Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

negative regulation of transcription, DNA-templated

regulation of macroautophagy

IDA

1 reference

9 May 2019

Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

regulation of histamine secretion by mast cell

NAS

1 reference

9 May 2019

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

negative regulation of neuron apoptotic process

IMP

1 reference

9 May 2019

miR-98-5p Acts as a Target for Alzheimer's Disease by Regulating Aβ Production Through Modulating SNX6 Expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

cellular response to amyloid-beta

IGI

1 reference

9 May 2019

miR-98-5p Acts as a Target for Alzheimer's Disease by Regulating Aβ Production Through Modulating SNX6 Expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

retrograde transport, endosome to Golgi

IGI

3 references

9 May 2019

Retromer: Structure, function, and roles in mammalian disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UNH7

Sorting nexin Vps5-like, C-terminal

IBA

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UNH7

Phox homologous domain

1 reference

stated in

InterPro Release 71.0