UFM1 specific ligase 1 (Q21123542)

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mammalian protein found in Homo sapiens

novel LZAP-binding protein
E3 UFM1-protein transferase 1
multiple alpha-helix protein located at ER
E3 UFM1-protein ligase 1
LZAP-binding protein
Regulator of CDK5RAP3 and DDRGK1
UFL1
regulator of C53/LZAP and DDRGK1

Language	Label	Description	Also known as
English	UFM1 specific ligase 1	mammalian protein found in Homo sapiens	novel LZAP-binding protein E3 UFM1-protein transferase 1 multiple alpha-helix protein located at ER E3 UFM1-protein ligase 1 LZAP-binding protein Regulator of CDK5RAP3 and DDRGK1 UFL1 regulator of C53/LZAP and DDRGK1

Statements

1 reference

13 November 2019

UniProt protein ID

E3 UFM1-protein ligase 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O94874

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

UFM1 transferase activity

determination method

1 reference

8 April 2019

A novel type of E3 ligase for the Ufm1 conjugation system

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

ligase activity

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94874&geneProductId=UniProtKB:O94874

determination method

protein binding

determination method

4 references

9 May 2019

A novel type of E3 ligase for the Ufm1 conjugation system

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

9 May 2019

A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

9 May 2019

A novel LZAP-binding protein, NLBP, inhibits cell invasion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

9 May 2019

Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

transferase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

determination method

3 references

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

endoplasmic reticulum membrane

determination method

1 reference

8 April 2019

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

determination method

1 reference

26 September 2017

Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94874&geneProductId=UniProtKB:O94874

determination method

endoplasmic reticulum

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

9 May 2019

A novel type of E3 ligase for the Ufm1 conjugation system

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

9 May 2019

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

neuron projection

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

determination method

1 reference

9 May 2019

Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

protein-containing complex

determination method

1 reference

9 May 2019

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

biological process

protein ufmylation

determination method

regulation of intracellular estrogen receptor signaling pathway

determination method

1 reference

9 May 2019

Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

response to endoplasmic reticulum stress

determination method

1 reference

8 April 2019

Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

regulation of protein localization

determination method

1 reference

9 May 2019

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

negative regulation of protein ubiquitination

determination method

1 reference

9 May 2019

A novel LZAP-binding protein, NLBP, inhibits cell invasion

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

protein K69-linked ufmylation

determination method

1 reference

8 April 2019

Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

osteoblast differentiation

determination method

1 reference

26 September 2017

Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94874&geneProductId=UniProtKB:O94874

determination method

positive regulation of cell population proliferation

determination method

1 reference

9 May 2019

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

response to L-glutamate

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method

1 reference

8 April 2019

A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

regulation of gene expression

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

negative regulation of NF-kappaB transcription factor activity

determination method

positive regulation of glial cell proliferation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

negative regulation of apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

osteoblast differentiation

determination method

1 reference

9 May 2019

Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94874

determination method

regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method

response to endoplasmic reticulum stress

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000358283

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000358283

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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