NKD inhibitor of WNT signaling pathway 2 (Q21123119)

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

growth factor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

6 references

8 April 2019

EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

8 April 2019

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

8 April 2019

EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

8 April 2019

Toward an understanding of the protein interaction network of the human liver

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

8 April 2019

PR72, a novel regulator of Wnt signaling required for Naked cuticle function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

8 April 2019

Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

ubiquitin protein ligase binding

IPI

1 reference

8 April 2019

EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

myosin heavy chain binding

IPI

1 reference

8 April 2019

Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

8 April 2019

Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q969F2&geneProductId=UniProtKB:Q969F2

Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane

lateral plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

basolateral plasma membrane

1 reference

8 April 2019

Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

8 April 2019

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

8 April 2019

Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

IDA

biological process

Wnt signaling pathway

1 reference

8 April 2019

positive regulation of protein processing

1 reference

8 April 2019

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

Golgi vesicle fusion to target membrane

IDA

1 reference

8 April 2019

Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

IMP

1 reference

8 April 2019

Myristoylated Naked2 antagonizes Wnt-beta-catenin activity by degrading Dishevelled-1 at the plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

protein localization to plasma membrane

1 reference

8 April 2019

Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

positive regulation of protein localization to plasma membrane

IMP

1 reference

8 April 2019

Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q969F2

negative regulation of Wnt signaling pathway

IDA

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q969F2&geneProductId=UniProtKB:Q969F2