Oxoglutarate dehydrogenase (Q21121770)

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mammalian protein found in Homo sapiens

oxoglutarate dehydrogenase (succinyl-transferring)
oxoglutarate decarboxylase
2-oxoglutarate dehydrogenase, mitochondrial
2-oxoglutarate dehydrogenase complex component E1
Alpha-ketoglutarate dehydrogenase
OGDC-E1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
testicular tissue protein Li 131

Language	Label	Description	Also known as
English	Oxoglutarate dehydrogenase	mammalian protein found in Homo sapiens	oxoglutarate dehydrogenase (succinyl-transferring) oxoglutarate decarboxylase 2-oxoglutarate dehydrogenase, mitochondrial 2-oxoglutarate dehydrogenase complex component E1 Alpha-ketoglutarate dehydrogenase OGDC-E1 OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) testicular tissue protein Li 131

Statements

1 reference

13 November 2019

UniProt protein ID

Thiamin diphosphate-binding fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02218

2-oxoglutarate dehydrogenase E1 component

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q02218

Dehydrogenase, E1 component domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transketolase-like, pyrimidine-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

2-oxoglutarate dehydrogenase E1 component, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

oxoglutarate dehydrogenase (NAD+) activity

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

oxidoreductase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

oxoglutarate dehydrogenase (succinyl-transferring) activity

determination method

6 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

heat shock protein binding

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

chaperone binding

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02218&geneProductId=UniProtKB:Q02218

determination method

mitochondrial membranes

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

determination method

4 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

oxoglutarate dehydrogenase complex

determination method

3 references

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

1 January 2018

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

biological process

glycolytic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

olfactory bulb mitral cell layer development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

thalamus development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

generation of precursor metabolites and energy

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

tangential migration from the subventricular zone to the olfactory bulb

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

NADH metabolic process

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

cerebellar cortex development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

pyramidal neuron development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02218&geneProductId=UniProtKB:Q02218

determination method

hippocampus development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

striatum development

determination method

1 reference

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

2-oxoglutarate metabolic process

determination method

3 references

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

1 January 2018

Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

1 January 2018

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

succinyl-CoA metabolic process

determination method

3 references

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

1 January 2018

Studies on the regulation of the human E1 subunit of the 2-oxoglutarate dehydrogenase complex, including the identification of a novel calcium-binding site.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

1 January 2018

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

histone succinylation

determination method

1 reference

8 April 2019

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

tricarboxylic acid cycle

determination method

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02218&geneProductId=UniProtKB:Q02218

determination method

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02218&geneProductId=UniProtKB:Q02218

determination method

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02218&geneProductId=UniProtKB:Q02218

determination method

tricarboxylic acid cycle

determination method

lysine catabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02218

determination method

2-oxoglutarate metabolic process

determination method

succinyl-CoA metabolic process

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000222673

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000222673

ENSP00000388084

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388084

ENSP00000392878

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000392878

ENSP00000388183

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388183

ENSP00000398576

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000398576

ENSP00000411830

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411830

ENSP00000414662

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000414662

ENSP00000486854

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486854

0 references

Microsoft Academic ID

0 references

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(7 entries)

dewiki Α-Ketoglutarat-Dehydrogenase E1
enwiki OGDH
frwiki Alpha-Cétoglutarate déshydrogénase
glwiki Alfa-cetoglutarato deshidroxenase
mswiki OGDH
ttwiki OGDH
ukwiki OGDH

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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