Protein tyrosine phosphatase 4A3 (Q21120525)

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mammalian protein found in Homo sapiens

PRL-R
PRL-3
protein-tyrosine phosphatase of regenerating liver 3
potentially prenylated protein tyrosine phosphatase
protein tyrosine phosphatase type IVA, member 3
protein tyrosine phosphatase type IVA 3
protein-tyrosine phosphatase 4a3
phosphatase of regenerating liver 3
PTP4A3

Language	Label	Description	Also known as
English	Protein tyrosine phosphatase 4A3	mammalian protein found in Homo sapiens	PRL-R PRL-3 protein-tyrosine phosphatase of regenerating liver 3 potentially prenylated protein tyrosine phosphatase protein tyrosine phosphatase type IVA, member 3 protein tyrosine phosphatase type IVA 3 protein-tyrosine phosphatase 4a3 phosphatase of regenerating liver 3 PTP4A3

Statements

1 reference

13 November 2019

UniProt protein ID

Protein-tyrosine phosphatase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75365

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Dual specificity phosphatase

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein tyrosine phosphatase activity

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75365&geneProductId=UniProtKB:O75365

determination method

prenylated protein tyrosine phosphatase activity

determination method

1 reference

8 April 2019

Mouse PRL-2 and PRL-3, two potentially prenylated protein tyrosine phosphatases homologous to PRL-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

phosphatase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

phosphoprotein phosphatase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

protein tyrosine/serine/threonine phosphatase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

protein binding

determination method

1 reference

8 April 2019

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

plasma membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

determination method

1 reference

27 March 2018

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75365&geneProductId=UniProtKB:O75365

determination method

determination method

1 reference

27 March 2018

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75365&geneProductId=UniProtKB:O75365

determination method

biological process

Notch signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

protein dephosphorylation

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

positive regulation of vascular permeability

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

regulation of vascular endothelial growth factor signaling pathway

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

dephosphorylation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

peptidyl-tyrosine dephosphorylation

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

positive regulation of NIK/NF-kappaB signaling

determination method

1 reference

8 April 2019

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

positive regulation of establishment of protein localization

determination method

1 reference

8 April 2019

PRL-3 activates NF-κB signaling pathway by interacting with RAP1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

cellular response to leukemia inhibitory factor

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

endothelial cell migration

determination method

3 references

8 April 2019

Protein-tyrosine phosphatase 4A3 (PTP4A3) promotes vascular endothelial growth factor signaling and enables endothelial cell motility

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75365

determination method

Protein-tyrosine phosphatase, catalytic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75365

Tyrosine specific protein phosphatases domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O75365

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000331730

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000331730

ENSP00000332274

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000332274

ENSP00000428758

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000428758

ENSP00000428976

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000428976

ENSP00000481205

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000481205

ENSP00000484500

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484500

ENSP00000487595

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487595

ENSP00000487610

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487610

ENSP00000487861

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487861

ENSP00000430332

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000430332

ENSP00000428725

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000428725

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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