Nudix hydrolase 3 (Q21119607)

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mammalian protein found in Homo sapiens

nucleoside diphosphate-linked moiety X motif 3
diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1
nudix (nucleoside diphosphate linked moiety X)-type motif 3
diphosphoinositol polyphosphate phosphohydrolase 1
NUDT3
3.6.1.-
nudix motif 3

Language	Label	Description	Also known as
English	Nudix hydrolase 3	mammalian protein found in Homo sapiens	nucleoside diphosphate-linked moiety X motif 3 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1 nudix (nucleoside diphosphate linked moiety X)-type motif 3 diphosphoinositol polyphosphate phosphohydrolase 1 NUDT3 3.6.1.- nudix motif 3

Statements

1 reference

13 November 2019

UniProt protein ID

NUDIX hydrolase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95989

NUDIX hydrolase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

NUDIX hydrolase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity

determination method

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

inositol diphosphate tetrakisphosphate diphosphatase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

determination method

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

diphosphoinositol-polyphosphate diphosphatase activity

determination method

3 references

27 March 2018

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

27 March 2018

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity

determination method

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity

determination method

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

determination method

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

magnesium ion binding

determination method

1 reference

8 April 2019

Crystal structure of human diphosphoinositol phosphatase 1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity

determination method

1 reference

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95989&geneProductId=UniProtKB:O95989

determination method

endopolyphosphatase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

bis(5'-adenosyl)-hexaphosphatase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

bis(5'-adenosyl)-pentaphosphatase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

m7G(5')pppN diphosphatase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

diphosphoinositol-polyphosphate diphosphatase activity

determination method

4 references

8 April 2019

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

8 April 2019

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

inositol diphosphate pentakisphosphate diphosphatase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

biological process

cell-cell signaling

determination method

1 reference

8 April 2019

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

diadenosine polyphosphate catabolic process

determination method

1 reference

8 April 2019

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

inositol phosphate metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

diphosphoinositol polyphosphate catabolic process

determination method

1 reference

8 April 2019

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

diadenosine pentaphosphate catabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

diadenosine hexaphosphate catabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

adenosine 5'-(hexahydrogen pentaphosphate) catabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

diphosphoinositol polyphosphate metabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95989

determination method

EC enzyme number

3.6.1.-

1 reference

14 November 2015

http://www.uniprot.org/uniprot/O95989.txt?version=144

NUDIX hydrolase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95989

NUDIX hydrolase, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O95989

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000476119

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476119

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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