LEM domain containing 3 (Q21119396)

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mammalian protein found in Homo sapiens

LEMD3/MKX fusion
integral inner nuclear membrane protein
LEMD3
MAN antigen 1
LEM domain-containing protein 3
inner nuclear membrane protein Man1

Language	Label	Description	Also known as
English	LEM domain containing 3	mammalian protein found in Homo sapiens	LEMD3/MKX fusion integral inner nuclear membrane protein LEMD3 MAN antigen 1 LEM domain-containing protein 3 inner nuclear membrane protein Man1

Statements

1 reference

13 November 2019

UniProt protein ID

RNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

Inner nuclear membrane protein Man1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

LEM/LEM-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

Nucleotide-binding alpha-beta plait domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

MAN1, RNA recognition motif, protein family

1 reference

based on heuristic

inferred from protein domain or family

LEM domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Man1/Src1, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

protein binding

determination method

3 references

8 April 2019

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

8 April 2019

Functional proteomics mapping of a human signaling pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

8 April 2019

Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

nucleic acid binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

chromatin DNA binding

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2U8&geneProductId=UniProtKB:Q9Y2U8

determination method

nuclear inner membrane

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

8 April 2019

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

nuclear membrane

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

integral component of nuclear inner membrane

determination method

3 references

10 September 2018

MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2U8&geneProductId=UniProtKB:Q9Y2U8

determination method

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2U8&geneProductId=UniProtKB:Q9Y2U8

determination method

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2U8&geneProductId=UniProtKB:Q9Y2U8

determination method

biological process

negative regulation of activin receptor signaling pathway

determination method

1 reference

8 April 2019

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

negative regulation of transforming growth factor beta receptor signaling pathway

determination method

1 reference

8 April 2019

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

negative regulation of BMP signaling pathway

determination method

1 reference

27 March 2018

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2U8&geneProductId=UniProtKB:Q9Y2U8

determination method

nuclear envelope organization

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

meiotic attachment of telomere to nuclear envelope

determination method

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2U8&geneProductId=UniProtKB:Q9Y2U8

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

nucleus organization

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

regulation of intracellular signal transduction

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2U8

determination method

negative regulation of BMP signaling pathway

determination method

Man1/Src1, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

MAN1, RNA recognition motif

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2U8

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000308369

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000308369

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

Sitelinks

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