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Down-regulator of transcription 1 (Q21118824)

From Wikidata

mammalian protein found in Homo sapiens

DR1
TATA-binding protein-associated phosphoprotein
protein Dr1
negative cofactor 2-beta
negative cofactor 2
NC2-beta

Language	Label	Description	Also known as
default for all languages	No label defined
English	Down-regulator of transcription 1	mammalian protein found in Homo sapiens	DR1 TATA-binding protein-associated phosphoprotein protein Dr1 negative cofactor 2-beta negative cofactor 2 NC2-beta

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01658

Transcription factor CBF/NF-Y/archaeal histone domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

TBP-class protein binding

determination method or standard

1 reference

27 February 2018

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

transcription factor binding

determination method or standard

1 reference

9 May 2019

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

protein binding

determination method or standard

4 references

9 May 2019

LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

Towards a proteome-scale map of the human protein–protein interaction network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

A protein domain-based interactome network for C. elegans early embryogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

transcription corepressor activity

determination method or standard

1 reference

27 February 2018

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

protein heterodimerization activity

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

1 reference

9 May 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

transcription coactivator activity

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

transcription corepressor activity

determination method or standard

TBP-class protein binding

determination method or standard

RNA polymerase II general transcription initiation factor activity

determination method or standard

1 reference

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

transcription corepressor activity

determination method or standard

3 references

9 May 2019

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

determination method or standard

negative cofactor 2 complex

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

biological process

regulation of transcription, DNA-templated

determination method or standard

1 reference

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

1 reference

27 February 2018

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

histone H3 acetylation

determination method or standard

1 reference

9 May 2019

Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

transcription, DNA-templated

determination method or standard

1 reference

27 February 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

chromatin remodeling

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

regulation of RNA polymerase II transcription preinitiation complex assembly

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

positive regulation of transcription by RNA polymerase II

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

RNA polymerase II preinitiation complex assembly

determination method or standard

1 reference

10 September 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

transcription by RNA polymerase II

determination method or standard

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01658&geneProductId=UniProtKB:Q01658

determination method or standard

negative regulation of transcription by RNA polymerase II

determination method or standard

3 references

9 May 2019

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01658

determination method or standard

Transcription factor CBF/NF-Y/archaeal histone domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01658

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000359290

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359290

ENSP00000359295

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359295

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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