Phosphatidylinositol-5-phosphate 4-kinase type 2 beta (Q21118288)

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mammalian protein found in Homo sapiens

1-phosphatidylinositol-4-phosphate kinase
PI(5)P 4-kinase type II beta
phosphatidylinositol 5-phosphate 4-kinase type II beta
PIP4K2B
phosphatidylinositol 5-phosphate 4-kinase type-2 beta
PIP4KII-beta
ptdIns(5)P-4-kinase isoform 2-beta
1-phosphatidylinositol 5-phosphate 4-kinase 2-beta
PTDINS(4)P-5-kinase
diphosphoinositide kinase 2-beta
phosphatidylinositol-4-phosphate 5-kinase, type II, beta

Language	Label	Description	Also known as
English	Phosphatidylinositol-5-phosphate 4-kinase type 2 beta	mammalian protein found in Homo sapiens	1-phosphatidylinositol-4-phosphate kinase PI(5)P 4-kinase type II beta phosphatidylinositol 5-phosphate 4-kinase type II beta PIP4K2B phosphatidylinositol 5-phosphate 4-kinase type-2 beta PIP4KII-beta ptdIns(5)P-4-kinase isoform 2-beta 1-phosphatidylinositol 5-phosphate 4-kinase 2-beta PTDINS(4)P-5-kinase diphosphoinositide kinase 2-beta phosphatidylinositol-4-phosphate 5-kinase, type II, beta

Statements

1 reference

13 November 2019

UniProt protein ID

Phosphatidylinositol-4-phosphate 5-kinase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P78356

Phosphatidylinositol-4-phosphate 5-kinase, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P78356

Phosphatidylinositol-4-phosphate 5-kinase, core domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

1-phosphatidylinositol-4-phosphate 5-kinase activity

determination method

1 reference

8 April 2019

A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

phosphatidylinositol phosphate kinase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

protein binding

determination method

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

1-phosphatidylinositol-3-phosphate 4-kinase activity

determination method

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P78356&geneProductId=UniProtKB:P78356

determination method

1-phosphatidylinositol-5-phosphate 4-kinase activity

determination method

4 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P78356&geneProductId=UniProtKB:P78356

determination method

7 November 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P78356&geneProductId=UniProtKB:P78356

determination method

7 November 2018

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site

http://www.ebi.ac.uk/QuickGO/annotations?protein=P78356&geneProductId=UniProtKB:P78356

determination method

7 November 2018

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P78356&geneProductId=UniProtKB:P78356

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

1-phosphatidylinositol-5-phosphate 4-kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

endoplasmic reticulum membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

plasma membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

1 reference

8 April 2019

PI(5)P regulates autophagosome biogenesis

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

endoplasmic reticulum

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

biological process

positive regulation of autophagosome assembly

determination method

1 reference

8 April 2019

PI(5)P regulates autophagosome biogenesis

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

cell surface receptor signaling pathway

determination method

1 reference

8 April 2019

A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

regulation of autophagy

determination method

1 reference

8 April 2019

PI(5)P regulates autophagosome biogenesis

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

phosphatidylinositol biosynthetic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

phosphatidylinositol phosphate biosynthetic process

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

regulation of phosphatidylinositol 3-kinase signaling

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

phospholipid metabolic process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78356

determination method

Phosphatidylinositol-4-phosphate 5-kinase, core

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P78356

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000480776

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000480776

ENSP00000482548

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482548

ENSP00000487739

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000487739

ENSP00000477549

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477549

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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