Syntrophin alpha 1 (Q21115228)

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mammalian protein found in Homo sapiens

TACIP1
SNTA1
syntrophin-1
dystrophin-associated protein A1, 59kDa, acidic component
acidic alpha 1 syntrophin
alpha-1-syntrophin
59 kDa dystrophin-associated protein A1 acidic component 1
pro-TGF-alpha cytoplasmic domain-interacting protein 1

Language	Label	Description	Also known as
English	Syntrophin alpha 1	mammalian protein found in Homo sapiens	TACIP1 SNTA1 syntrophin-1 dystrophin-associated protein A1, 59kDa, acidic component acidic alpha 1 syntrophin alpha-1-syntrophin 59 kDa dystrophin-associated protein A1 acidic component 1 pro-TGF-alpha cytoplasmic domain-interacting protein 1

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

sodium channel regulator activity

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

nitric-oxide synthase binding

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

transmembrane transporter binding

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

structural molecule activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

calmodulin binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

protein binding

determination method

3 references

8 April 2019

MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

8 April 2019

Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

8 April 2019

Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

PDZ domain binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

lateral plasma membrane

determination method

1 reference

8 April 2019

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

neuromuscular junction

determination method

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13424&geneProductId=UniProtKB:Q13424

determination method

plasma membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

intracellular anatomical structure

determination method

1 reference

1 January 2018

MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13424&geneProductId=UniProtKB:Q13424

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

syntrophin complex

determination method

1 reference

8 April 2019

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

protein-containing complex

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

dystrophin-associated glycoprotein complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

determination method

3 references

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

biological process

muscle contraction

determination method

1 reference

8 April 2019

The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

negative regulation of peptidyl-cysteine S-nitrosylation

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

ventricular cardiac muscle cell action potential

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

regulation of heart rate

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

regulation of sodium ion transmembrane transport

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

regulation of ventricular cardiac muscle cell membrane repolarization

determination method

1 reference

8 April 2019

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13424

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13424

pleckstrin homology domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13424

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000217381

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000217381

PDB structure ID

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q61234.txt?version=144

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q61234.txt?version=144

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q61234.txt?version=144

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q61234.txt?version=144

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q61234.txt?version=144

1 reference

10 November 2015

http://www.uniprot.org/uniprot/Q61234.txt?version=144

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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