MMS19 homolog, cytosolic iron-sulfur assembly component (Q21114949)

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mammalian protein found in Homo sapiens

homolog of yeast MMS19
MMS19-like (MET18 homolog, S. cerevisiae)
MMS19 nucleotide excision repair protein homolog
MMS19 nucleotide excision repair homolog
MET18 homolog
MMS19 cytosolic iron-sulfur assembly component
MMS19-like protein
MMS19

Language	Label	Description	Also known as
English	MMS19 homolog, cytosolic iron-sulfur assembly component	mammalian protein found in Homo sapiens	homolog of yeast MMS19 MMS19-like (MET18 homolog, S. cerevisiae) MMS19 nucleotide excision repair protein homolog MMS19 nucleotide excision repair homolog MET18 homolog MMS19 cytosolic iron-sulfur assembly component MMS19-like protein MMS19

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein-macromolecule adaptor activity

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

transcription coactivator activity

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

protein binding

determination method

6 references

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Next-generation sequencing to generate interactome datasets

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

signaling receptor complex adaptor activity

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

estrogen receptor binding

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96T76&geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

transcription factor TFIIH holo complex

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

3 references

8 April 2019

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

8 April 2019

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

8 April 2019

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

8 April 2019

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

3 references

9 May 2019

Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

3 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

1 reference

9 May 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

4 references

9 May 2019

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q96T76&geneProductId=UniProtKB:Q96T76

determination method

DNA metabolic process

determination method

1 reference

9 May 2019

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

phosphorelay signal transduction system

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

response to hormone

determination method

1 reference

9 May 2019

The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

nucleotide-excision repair

determination method

transcription, DNA-templated

determination method

transcription, DNA-templated

determination method

1 reference

9 May 2019

Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

positive regulation of double-strand break repair via homologous recombination

determination method

1 reference

8 April 2019

Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

positive regulation of signal transduction

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

determination method

3 references

9 May 2019

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

chromosome segregation

determination method

3 references

9 May 2019

MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

iron-sulfur cluster assembly

determination method

3 references

9 May 2019

MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

positive regulation of transcription, DNA-templated

determination method

protein maturation by iron-sulfur cluster transfer

determination method

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q96T76

determination method

positive regulation of double-strand break repair via homologous recombination

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000320059

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000320059

ENSP00000348097

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000348097

ENSP00000359818

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000359818

ENSP00000395045

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000395045

ENSP00000412698

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000412698

ENSP00000413801

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000413801

ENSP00000391765

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000391765

ENSP00000393929

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393929

ENSP00000400028

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000400028

ENSP00000402819

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000402819

ENSP00000409425

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000409425

ENSP00000410008

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000410008

ENSP00000415326

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000415326

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