Phosphatidylinositol 3-kinase catalytic subunit type 3 (Q21112836)

Protein kinase-like domain superfamily

1 reference

C2 domain superfamily

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily

1 reference

Phosphatidylinositol kinase family

1 reference

Armadillo-type fold

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family

1 reference

Phosphatidylinositol 3-kinase, C2 domain, protein family

1 reference

Phosphoinositide 3-kinase, accessory (PIK) domain, protein family

1 reference

Phosphatidylinositol 3/4-kinase, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

protein kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1-phosphatidylinositol-3-kinase activity

6 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

31 October 2017

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

31 October 2017

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

25 references

8 April 2019

Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in gastric cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Human VPS34 and p150 are Rab7 Interacting Partners

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Network organization of the human autophagy system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

NRBF2 regulates macroautophagy as a component of Vps34 Complex I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Identification of a candidate therapeutic autophagy-inducing peptide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

A kinase-independent role for EGF receptor in autophagy initiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

The VMP1-Beclin 1 interaction regulates autophagy induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol 3-kinase activity

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1-phosphatidylinositol-3-kinase activity

IDA

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

phagocytic vesicle membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

31 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

IDA

phagophore assembly site

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol 3-kinase complex, class III, type I

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol 3-kinase complex, class III, type II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

regulation of cytokinesis

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

31 October 2017

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

IMP

endosome organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol phosphate biosynthetic process

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

early endosome to late endosome transport

1 reference

8 April 2019

Human VPS34 and p150 are Rab7 Interacting Partners

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol biosynthetic process

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

toll-like receptor 9 signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

regulation of protein secretion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

protein localization to phagophore assembly site

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

cellular response to starvation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

autophagy of peroxisome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8NEB9

phosphatidylinositol-mediated signaling

interleukin-7-mediated signaling pathway

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8NEB9&geneProductId=UniProtKB:Q8NEB9

TAS

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016