G protein-coupled receptor 55 (Q21110942)

http://www.ebi.ac.uk/interpro/protein/Q9Y2T6

InterPro Release 71.0

reference URL

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

cannabinoid receptor activity

1 reference

5 June 2018

Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2T6&geneProductId=UniProtKB:Q9Y2T6

G protein-coupled receptor activity

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2T6&geneProductId=UniProtKB:Q9Y2T6

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2T6&geneProductId=UniProtKB:Q9Y2T6

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2T6&geneProductId=UniProtKB:Q9Y2T6

5 June 2018

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2T6&geneProductId=UniProtKB:Q9Y2T6

1 reference

31 October 2017

G protein-coupled receptor activity

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

integral component of plasma membrane

cell component

TAS

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

1 reference

8 April 2019

integral component of plasma membrane

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

TAS

8 April 2019

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

positive regulation of Rho protein signal transduction

biological process

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

4 references

8 April 2019

TAS

8 April 2019

Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

activation of phospholipase C activity

1 reference

5 June 2018

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2T6&geneProductId=UniProtKB:Q9Y2T6

bone resorption

1 reference

8 April 2019

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

negative regulation of osteoclast differentiation

1 reference

8 April 2019

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

1 reference

8 April 2019

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

cannabinoid signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

activation of phospholipase C activity

positive regulation of Rho protein signal transduction

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2T6

physically interacts with

glyceryl 2-arachidonate

1 reference

729

2-Arachidonyl glyceryl ether

17 August 2016

1 reference

5545

17 August 2016

1 reference

3317

17 August 2016

1 reference

2364

17 August 2016

1 reference

2424

17 August 2016

1 reference

731

17 August 2016

1 reference

5558

17 August 2016

oleic monoethanolamide

1 reference

2661

17 August 2016

1 reference

3622

17 August 2016

1 reference

5525

O-arachidonoyl ethanolamine

17 August 2016

1 reference

5554

17 August 2016

1 reference

4150

17 August 2016

1 reference

6577

17 August 2016

1 reference

743

GPCR, rhodopsin-like, 7TM

17 August 2016

has part(s)

1 reference