Dimethylarginine dimethylaminohydrolase 1 (Q21110855)

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mammalian protein found in Homo sapiens

DDAHI
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
dimethylargininase-1
DDAH1
epididymis secretory protein Li 16
NG, NG-dimethylarginine dimethylaminohydrolase

Language	Label	Description	Also known as
English	Dimethylarginine dimethylaminohydrolase 1	mammalian protein found in Homo sapiens	DDAHI N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 dimethylargininase-1 DDAH1 epididymis secretory protein Li 16 NG, NG-dimethylarginine dimethylaminohydrolase

Statements

1 reference

13 November 2019

UniProt protein ID

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O94760

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

catalytic activity

determination method

1 reference

8 April 2019

Purification, cDNA cloning and expression of human NG,NG-dimethylarginine dimethylaminohydrolase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

amino acid binding

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

dimethylargininase activity

determination method

5 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

26 September 2017

Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

dimethylargininase activity

determination method

6 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

1 January 2018

Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

dimethylargininase activity

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

extracellular exosome

determination method

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

26 September 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

biological process

positive regulation of nitric oxide biosynthetic process

determination method

regulation of nitric-oxide synthase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

arginine metabolic process

determination method

1 reference

26 September 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O94760&geneProductId=UniProtKB:O94760

determination method

positive regulation of angiogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

nitric oxide mediated signal transduction

determination method

1 reference

8 April 2019

Purification, cDNA cloning and expression of human NG,NG-dimethylarginine dimethylaminohydrolase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

arginine catabolic process

determination method

3 references

8 April 2019

Purification, cDNA cloning and expression of human NG,NG-dimethylarginine dimethylaminohydrolase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

negative regulation of cell population proliferation

determination method

1 reference

8 April 2019

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

negative regulation of vascular permeability

determination method

1 reference

8 April 2019

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

negative regulation of cellular response to hypoxia

determination method

1 reference

8 April 2019

miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

citrulline metabolic process

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

positive regulation of nitric oxide biosynthetic process

determination method

4 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O94760

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000284031

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000284031

ENSP00000411189

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000411189

ENSP00000439045

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000439045

ENSP00000488725

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000488725

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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